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The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa

NCT05413148 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 135

Last updated 2022-09-07

No results posted yet for this study

Summary

This clinical trial aims to study the efficacy of umbilical cord-derived mesenchymal stem cells and their exosomes in the treatment of retinitis pigmentosa. The participants will be randomized into 3 groups. Functional and structural parameters will be compared before and after the injections and also will be compared among the groups to reveal whether stem cell and their exosomes are more effective than placebo.

Conditions

Interventions

BIOLOGICAL

Subtenon injection of Wharton jelly derived mesenchymal stem cells

Single subtenon's injection for single eye

BIOLOGICAL

Subtenon injection of Wharton jelly derived mesenchymal stem cell exosomes

Single subtenon's injection for single eye

OTHER

Placebo

Single Subtenon injection of saline for a single eye

Sponsors & Collaborators

  • TC Erciyes University

    lead OTHER

Principal Investigators

  • Kuddusi ERKILIÇ, Professor · Erciyes University Medical Faculty

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-05
Primary Completion
2023-07-01
Completion
2023-12-15

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05413148 on ClinicalTrials.gov