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miRNA in Patients With Thoracic, Abdominal and Intracranial Aneurysms

NCT05382611 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2022-05-19

No results posted yet for this study

Summary

To assess the expression of miRNA in patients with TAA, AAA in aneurysmatic tissue and to compare this expression with the healthy tissue in the same patient.

In the same cohort, to asses the presence of miRNA in plasma and to compare with the control group.

Over the period of three years,to follow subjects in order to assess if the presence of certain miRNAs speeds up or slows down the progression of disease.

In patients with intracranial aneurysms to detect miRNA in plasma especially in patients with familial occurrence.

Conditions

  • Vascular Aneurysm

Interventions

DIAGNOSTIC_TEST

ngs next generation sequencing

the samples from aneurysmatic tissue and healthy aortic tissue will be investigated using NGS

Sponsors & Collaborators

  • Czech Academy of Sciences

    collaborator OTHER

  • Na Homolce Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-05-19
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05382611 on ClinicalTrials.gov