Study of AT-752 in Healthy Subjects in a Dengue Human Challenge Model
NCT05366439 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2023-04-21
Summary
This study will assess the safety and antiviral activity of AT-752 in healthy subjects in a Dengue Human Challenge Model
Conditions
- Dengue
Interventions
- DRUG
-
AT-752
Parallel Assignment
- DRUG
-
Placebo Comparator
Parallel Assignment
Sponsors & Collaborators
-
Atea Pharmaceuticals, Inc.
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-04-22
- Primary Completion
- 2023-03-16
- Completion
- 2023-03-16
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Study of JNJ-64281802 in Participants With Confirmed Dengue Fever
NCT04906980 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of AV-1 Against Dengue Virus 3 (DENV-3) Infection
NCT06799741 ·Status: COMPLETED ·Phase: PHASE2
-
Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults
NCT04723394 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19
NCT04889040 ·Status: TERMINATED ·Phase: PHASE3
-
AZD7442 - a Potential Combination Therapy for the Prevention and Treatment of COVID-19
NCT04507256 ·Status: COMPLETED ·Phase: PHASE1
-
An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge
NCT05048875 ·Status: COMPLETED ·Phase: PHASE2
-
To Evaluate the Efficacy and Safety of TG-1000 Compared With Placebo in Adult Patients With Acute Uncomplicated Influenza Virus Infection
NCT04706468 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever
NCT06006559 ·Status: RECRUITING ·Phase: PHASE2
-
Study of mRNA Vaccine Formulation Against COVID-19 in Healthy Adults 18 Years of Age and Older
NCT04798027 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study of Balapiravir in Patients With Dengue Virus Infection
NCT01096576 ·Status: COMPLETED ·Phase: PHASE1
-
A Trial of Remdesivir in Adults With Severe COVID-19
NCT04257656 ·Status: TERMINATED ·Phase: PHASE3
-
Phase III Double-blind, Placebo-controlled Study of AZD7442 for Post- Exposure Prophylaxis of COVID-19 in Adults
NCT04625972 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Preliminary Efficacy Study of GX-I7 in Patients With COVID-19
NCT04730427 ·Status: TERMINATED ·Phase: PHASE1
-
Effectiveness of mRNA-1273 Variant-Containing Vaccine Formulation Against Severe Outcomes in Adults Aged 50-64 Years Without Risk Factors for Severe COVID-19
NCT07279766 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Study on Safety and Clinical Efficacy of AZVUDINE in Initial Stage COVID-19 Patients (SARS-CoV-2 Infected)
NCT05033145 ·Status: COMPLETED ·Phase: PHASE3
-
EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19
NCT04960202 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression
NCT05947812 ·Status: UNKNOWN ·Phase: PHASE2
-
Dose-Confirmation Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1273 COVID-19 Vaccine in Adults Aged 18 Years and Older
NCT04405076 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of Efficacy of CR8020 and CR6261, Monoclonal Antibodies, Against Influenza Infection
NCT01992276 ·Status: WITHDRAWN ·Phase: PHASE2
-
Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)
NCT04470622 ·Status: TERMINATED ·Phase: PHASE2
-
Study of VIR-2482 in Healthy Volunteers
NCT04033406 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Trial of Efficacy and Safety of Oral Drug in Adult Patients With COVID-19
NCT05365321 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Clinical Trial to Evaluate the Safety and Efficacy of ATR-002 in Adult Hospitalized Patients With COVID-19
NCT04776044 ·Status: TERMINATED ·Phase: PHASE2
-
Clinical Trials to Assess Safety and Efficacy of DWRX2003 Combination With Remdesivir in Moderate to Severe COVID-19 Patients.
NCT05226533 ·Status: TERMINATED ·Phase: PHASE2
-
Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection
NCT05897541 ·Status: COMPLETED ·Phase: PHASE3