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Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients

NCT05364216 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 92

Last updated 2023-08-01

No results posted yet for this study

Summary

To investigate the effect of ultrasound-guided thoracic paravertebral nerve block on postoperative acute and chronic pain and cognitive function in elderly patients with thoracoscopic partial lung resection.

Conditions

  • Postoperative Cognitive Dysfunction
  • Acute Postoperative Pain
  • Chronic Postsurgical Pain

Interventions

BEHAVIORAL

Measurement of cognitive function

Patients undergoing thoracoscopic surgery underwent general anesthesia.MMSE and MoCA were assessed at one day before surgery, one day after surgery, and three months after surgery

PROCEDURE

Thoracic paravertebral block

The patient was placed in lateral supine position, and the T5 spinous process was moved 2 to 3 cm laterally to the operative side as the puncture point, and the pleura and T5 transverse process were observed, and the paraspinal space was observed on the lower lateral side of the transverse process. Using in-plane technique, the needle position was adjusted under ultrasound visualization to reach the paraspinal space. 20ml 0.375% ropivacaine was injected into the suction syringe when there was no blood or gas, and the drug liquid could be seen spreading outside the pleura. "Landscape sign" appeared, indicating successful block

BEHAVIORAL

The assessment of cognitive function

Participants were assessed for MMSE and MoCA at the same period as the group C

Sponsors & Collaborators

  • The First Hospital of Qinhuangdao

    lead OTHER_GOV

Principal Investigators

  • Qinshuang Liu, master · The First hosptial of Qinhuangdao

  • Linyu Shi, master · The First hosptial of Qinhuangdao

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-05-12
Primary Completion
2023-02-28
Completion
2023-05-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05364216 on ClinicalTrials.gov