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Atopic Dermatitis: Sub-Saharan Africa vs. Central Europe

NCT05363904 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 240

Last updated 2025-07-09

No results posted yet for this study

Summary

Many people are affected by atopic dermatitis (AD) worldwide. However, clinical studies on AD in Sub-Saharan Africa are rare and there is a lack of knowledge about possible differences in pathogenesis between European and African AD.

This study will collect clinical and laboratory data with the aim to compare clinical characteristics and immune responses in AD patients in Sub-Saharan Africa and Central Europe. Furthermore, relevant allergens as well as the nasal, skin and gut micro- and mycobiome will be investigated.

Conditions

Interventions

OTHER

Observation

Questionnaires, Clinical Scores, Biomaterial Sampling

Sponsors & Collaborators

  • Regional Dermatology Training Centre (RDTC), Moshi, Tanzania

    collaborator UNKNOWN

  • University Hospital Joseph Raseta Befelatanana in Antananarivo, Madagascar

    collaborator UNKNOWN

  • University of Zurich

    lead OTHER

Principal Investigators

  • Marie-Charlotte Brüggen, Prof. · University of Zurich

  • Daudi Mavura, Prof. · RDTC Moshi

  • John Masenga, Prof. · RDTC Moshi

  • Fandresena Sendrasoa, Dr. · University Hospital Joseph Raseta Befelatanana

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-30
Primary Completion
2025-03-12
Completion
2025-03-12

Countries

  • Madagascar
  • Switzerland
  • Tanzania

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05363904 on ClinicalTrials.gov