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Effects of a Single Dose of Amisulpride on Functional Brain Changes

NCT05347199 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 127

Last updated 2023-11-24

No results posted yet for this study

Summary

This study is designed to investigate effects of a single dose of amisulpride on functional brain changes during reward- and motivation-related processing and at rest in healthy volunteers (HV) and in patients with Major Depressive Disorder (MDD).

Conditions

Interventions

DRUG

Amisulpride Pill

Two single low doses amisulpride (100 mg); orally

DRUG

Placebo

two doses, orally

Sponsors & Collaborators

  • Charité Research Organisation GmbH

    collaborator OTHER

  • Boehringer Ingelheim

    collaborator INDUSTRY

  • Simone Grimm

    lead OTHER

Principal Investigators

  • Christian Keicher, Dr. med. · Charite University, Berlin, Germany

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-05-17
Primary Completion
2023-09-18
Completion
2023-09-25

Countries

  • Germany

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05347199 on ClinicalTrials.gov