The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma
NCT05344027 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35
Last updated 2023-03-08
Summary
This work will evaluate the effects of mitotane treatment on serum protein concentrations in patients treated for ACC with mitotane therapy and compare them to patients with an adrenal neoplasm and pregnant cohort. All of the individuals were treated at King's Hospital between April 2019 and June 2020. Proteins which will be evaluated during this study, include CBG and TBG.
Conditions
- Adrenocortical Carcinoma
Interventions
- DRUG
-
Mitotane
Individuals within the intervention group were on mitotane therapy as part of their ACC treatment.
Sponsors & Collaborators
-
King's College Hospital NHS Trust
lead OTHER
Eligibility
- Min Age
- 19 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-04-11
- Primary Completion
- 2023-01-30
- Completion
- 2023-03-01
- FDA Drug
- Yes
Countries
- United Kingdom
Study Locations
More Related Trials
-
Investigating Utility of ctDNA and Tumour Evolution in Advanced Thyroid Cancer
NCT05837260 ·Status: RECRUITING
-
A Pilot Study Utilizing Proteomic and Genomic Profiling for Patients With Metastatic Breast Cancer
NCT01919749 ·Status: COMPLETED ·Phase: NA
-
Optimal Methods of Disease Progression and Survival Analysis in Children and Adults Patients With Adrenocortical Cancer (ACC)
NCT04358107 ·Status: ACTIVE_NOT_RECRUITING
-
Detection of Germline and Somatic Pathogenic Variants in Patients With de Novo Metastatic Breast Cancer
NCT05758948 ·Status: UNKNOWN
-
c-MET Inhibitor in Advanced Solid Tumors With c-MET Gene Aberration
NCT05882292 ·Status: RECRUITING ·Phase: PHASE2
-
Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate
NCT01209299 ·Status: COMPLETED
-
Biopsies of Cancer Patients for Tumor Molecular Characterization
NCT01061944 ·Status: COMPLETED
-
Towards an Easy-to-use Adrenal Cancer/Tumor Identity Card
NCT02672020 ·Status: COMPLETED ·Phase: NA
-
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·Status: RECRUITING
-
Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells
NCT04628806 ·Status: UNKNOWN
-
Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women
NCT04291950 ·Status: WITHDRAWN
-
Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Biliary Tract Cancer Recurrence Surveillance
NCT06653127 ·Status: RECRUITING
-
Diagnosing Thyroid Cancer Using a Blood Test
NCT01586520 ·Status: COMPLETED
-
Implementation of the Methylome in the Characterization of Solid Tumors
NCT07268066 ·Status: RECRUITING
-
Molecular Analysis of the Sloane Project
NCT05868252 ·Status: UNKNOWN
-
Utilization of the OncoCEE™ Platform to Evaluate Selected Biomarker Alterations in CTCs Isolated From Patients With MBC
NCT02436772 ·Status: COMPLETED
-
Study of Proteins in Head and Neck Cancer Cells
NCT00896948 ·Status: COMPLETED
-
Liquid Biopsy of Head and Neck Cancer Patients in Blood and Saliva
NCT05122507 ·Status: UNKNOWN
-
Study of Blood Samples From Patients With Malignant Melanoma, Metastatic Breast Cancer, Advanced Lung Cancer, Pancreatic Cancer, or Colorectal Cancer.
NCT00974610 ·Status: COMPLETED
-
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
NCT03707574 ·Status: COMPLETED
-
Chemotherapy on Methylation Patterns in Breast Tumor Tissue Correlating With Clinical Response and Outcomes
NCT00698477 ·Status: UNKNOWN
-
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome
NCT04431024 ·Status: RECRUITING
-
Implementing Precision Medicine in cOmmunity HospiTALs
NCT05283044 ·Status: RECRUITING ·Phase: NA
-
Morehouse Total Cancer Care Protocol
NCT04804878 ·Status: RECRUITING
-
Registry Study for Personalized Cancer Therapy
NCT02508662 ·Status: COMPLETED