TAS-102 With or Without Celecoxib in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
NCT05343013 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2026-03-06
Summary
To measure the level of circulating tumor DNA (ctDNA) in the blood of colorectal cancer patients after 6 months of receiving TAS-102 therapy. ctDNA is genetic material from tumor cells that can be found and measured in the blood.
Conditions
Interventions
- DRUG
-
TAS-102
GIven by PO
Sponsors & Collaborators
-
Taiho
collaborator UNKNOWN -
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Alisha Bent, MD · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-06
- Primary Completion
- 2027-05-15
- Completion
- 2027-05-15
- FDA Drug
- Yes
Countries
- United States
Study Locations
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