A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers
NCT05337735 · Status: SUSPENDED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 140
Last updated 2026-05-04
Summary
To test the safety of and effectiveness of XmAb20717 for participants with advanced rare cancers.
Conditions
- Microsatellite High Cancers
- Peritoneal Mesothelioma
- Extrapulmonary High Grade
- Neuroendocrine Carcinomas
- Cervical Carcinoma
- Hodgkin's Lymphoma
- Pleural Mesothelioma
- Small Cell Lung Cancer
Interventions
- DRUG
-
XmAb20717
Given by vein (IV)
Sponsors & Collaborators
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Arvind Nageshwara Dasaru, MD · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-08-05
- Primary Completion
- 2026-12-30
- Completion
- 2026-12-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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