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Cataract Surgery and Inflammation - the Role for Preoperative NSAIDs (Pre-CIN)

NCT05331690 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 500

Last updated 2022-12-01

No results posted yet for this study

Summary

The pre-CIN trial is a randomized clinical three-arm trial comparing inflammation and cystoid macular edema for the medication regimens preoperative and postoperative topical NSAIDs to only postoperative topical NSAIDs to postoperative topical NSAIDs and steroids in patients undergoing cataract surgery.

Conditions

  • Cataract Surgery

Interventions

DRUG

Nepafenac Ophthalmic

Topical nepafenac (Nevanac) 3 mg/ml starter the day before surgery

DRUG

Nepafenac Ophthalmic

Topical nepafenac (Nevanac) 3 mg/ml started the day after surgery

DRUG

Dexamethasone Ophthalmic

Topical dexamethasone 1 mg/ml (Spersadex) started the day after surgery

Sponsors & Collaborators

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Olav Kristianslund, MD PhD · Department of Ophthalmology, Oslo University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-25
Primary Completion
2023-08-31
Completion
2023-12-31

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05331690 on ClinicalTrials.gov