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How Does Platelet Dose Impact Clinical Outcomes After PRP Treatment?

NCT05330689 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL

Last updated 2024-03-26

No results posted yet for this study

Summary

The purpose of this study is to determine which platelet rich plasma (PRP) injection dosage provides the most improvement in a patient's knee pain level at 26 weeks post-injection.

Conditions

  • Osteoarthritis, Knee

Interventions

BIOLOGICAL

PRP injection dose (<5 billion platelets)

PRP injection with a dose of platelets that is less than 5 billion platelets

BIOLOGICAL

PRP injection dose (between 5 and <10 billion platelets)

PRP injection with a dose of platelets that is between 5 and \<10 billion platelets

BIOLOGICAL

PRP injection dose (between 10 and <20 billion platelets)

PRP injection with a dose of platelets that is between 10 and \<20 billion platelets

BIOLOGICAL

PRP injection dose (20 billion or greater platelets)

PRP injection with a dose of platelets that is 20 billion platelets or greater

OTHER

Saline injection control

Saline control

Sponsors & Collaborators

  • Vanderbilt University Medical Center

    lead OTHER

Principal Investigators

  • Leon Scott, MD · Vanderbilt University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-06
Primary Completion
2022-09-07
Completion
2022-09-07
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05330689 on ClinicalTrials.gov