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Transcutaneous Auricular Vagus Nerve Stimulation to Enhance Motor Learning

NCT05316519 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 4

Last updated 2024-05-09

No results posted yet for this study

Summary

Vagus nerve stimulation (VNS) activates neural pathways leading to the release of chemicals that promote plasticity and learning. Previous work has shown that the auricular branch of the vagus nerve innervates landmarks on the external ear. Work from the PI's laboratory has shown that electrical current applied to the external ear activates neural pathways implicated in the therapeutic effects of VNS. The broad objective of this project is to better understand physiological mechanisms that are modulated by auricular stimulation and its potential to enhance motor learning.

Conditions

  • Neurological Injury
  • Motor Disorders
  • Paresis

Interventions

OTHER

Transcutaneous Vagus Nerve Stimulation

Visuomotor task training with transcutaneous stimulation targeting landmark that activates biomarker

Sponsors & Collaborators

  • VA Pittsburgh Healthcare System

    lead FED

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-06-01
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05316519 on ClinicalTrials.gov