Intralesional Versus Intramuscular Methotrexate for Non-melanoma Skin Cancers
NCT05315128 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2022-04-07
Summary
to compare the effectiveness and safety of intralesional vs. systemic MTX in NMSC management
Conditions
Interventions
- DRUG
-
Methotrexate
A randomized comparative effectiveness clinical trial
Sponsors & Collaborators
-
Zagazig University
lead OTHER_GOV
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-07-06
- Primary Completion
- 2021-08-10
- Completion
- 2021-12-06
Countries
- Egypt
Study Locations
More Related Trials
-
MLN0128 in Recurrent/Metastatic Merkel Cell Carcinoma
NCT02514824 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
How Microbes and Metabolism May Predict Skin Cancer Immunotherapy Outcomes
NCT03370861 ·Status: TERMINATED
-
To Explore the Efficacy and Safety of SHR-1701 Combined With Temozolomide in the Treatment of Advanced Melanoma
NCT05106023 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Study Protocol for Cutaneous SCC for Immunocompromised Patients
NCT06615635 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Patient-led Surveillance Compared to Clinician-led Surveillance in People Treated for Localised Melanoma.
NCT03581188 ·Status: COMPLETED ·Phase: NA
-
Intratumoral Injection Of Alpha-Gal Glycosphingolipids
NCT00668512 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Therapy of Topical Imiquimod Plus Multipeptide Vaccination for Cutaneous Metastases of Melanoma
NCT01264731 ·Status: COMPLETED ·Phase: PHASE1
-
Intratumoral Targeted Hyperthermia Therapy (THT) for Stage 3C/3D/4M1 Cutaneous Metastatic Melanoma
NCT06894407 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic
NCT02094872 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Lenvatinib Plus Pembrolizumab in Merkel Cell Carcinoma
NCT04869137 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 2 Study Evaluating the Safety and Efficacy of Microneedle-mediated Delivery of Doxorubicin (D-MNA) in Patients With Nodular Basal Cell Carcinoma.
NCT06608238 ·Status: COMPLETED ·Phase: PHASE2
-
MEK Inhibitor FCN-159 To Treat Advanced Melanoma With NRAS-aberrant (Ia) and NRAS-mutant (Ib)or NF1-mutant(1b)
NCT03932253 ·Status: SUSPENDED ·Phase: PHASE1
-
A Study of Neoadjuvant Therapy With BCD-217 (Nurulimab + Prolgolimab) in Patients With Resectable Stage III Skin Melanoma
NCT05751928 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Interactive Tailored Website to Promote Sun Protection and Skin Self-Check Behaviors in Patients With Melanoma
NCT03028948 ·Status: COMPLETED ·Phase: NA
-
Study of the Combination of CM082 With JS001 in Patients With Advanced Mucosal Melanoma.
NCT03602547 ·Status: UNKNOWN ·Phase: PHASE2
-
AMT-253 in Patients With Advanced Solid Tumours
NCT06209580 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of RC48-ADC in Advanced Melanoma Subjects With HER2 Variant (Mutation, Amplification, Overexpression)
NCT05135715 ·Status: RECRUITING ·Phase: PHASE2
-
Phase I/II Study of Chemo-Immunotherapy Combination in Melanoma Patients
NCT00559026 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety and Efficacy of MGD013 in Patients With Melanoma
NCT04653038 ·Status: TERMINATED ·Phase: PHASE1
-
To Explore the Efficacy and Safety of Camrelizumab Combined With SHR1020 in the Treatment of Advanced Melanoma
NCT05051865 ·Status: UNKNOWN ·Phase: PHASE2
-
Relevance of Imiquimod as Neo-adjuvant Treatment to Reduce Excision Size and the Risk of Intralesional Excision in Lentigo Malignant of the Face
NCT01720407 ·Status: COMPLETED ·Phase: PHASE3
-
GSK1120212 vs Chemotherapy in Advanced or Metastatic BRAF V600E/K Mutation-positive Melanoma
NCT01245062 ·Status: COMPLETED ·Phase: PHASE3
-
Study in Patients With Solid Tumor Regarding Access to Dermo-cosmetics and Aesthetic Solutions
NCT05907551 ·Status: UNKNOWN
-
Chemo-immunotherapy in Patients With Resectable Merkel Cell Carcinoma Prior to Surgery
NCT05594290 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma
NCT07280832 ·Status: RECRUITING ·Phase: PHASE1/PHASE2