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A Trial to Assess Steviol Glycosides on Acute Appetite Hormone Release

NCT05287906 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 69

Last updated 2024-09-19

No results posted yet for this study

Summary

The objectives of this trial are to assess the effects of steviol glycoside alone or in combination with a glycemic carbohydrate on blood glucose and endocrine and gut hormone secretion vs. water and glucose in individuals with normal weight, overweight and type 2 diabetes mellitus (T2DM).

Conditions

Interventions

OTHER

Water

Each subject will receive one control and three treatments in the crossover design. The control contains water only.

OTHER

Glucose

Each subject will receive one control and three treatments in the crossover design. The glucose contains water and glucose.

OTHER

Steviol Glycosides

Each subject will receive one control and three treatments in the crossover design. The Steviol Glycoside beverage contains water and steviol glycosides.

OTHER

Steviol Glycosides plus glucose

Each subject will receive one control and three treatments in the crossover design. The Steviol Glycoside plus glucose beverage contains water, glucose, and steviol glycosides.

OTHER

Rebaudioside A

A leaf-based, extracted stevia product to compare to the Eversweet in the normal weight group only. The Rebaudioside A contains water and rebaudioside A.

Sponsors & Collaborators

  • Cargill

    collaborator INDUSTRY

  • Midwest Center for Metabolic and Cardiovascular Research

    lead OTHER

Principal Investigators

  • Kevin Maki, PhD · MB Clinical Research & Consulting, LLC

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-04-15
Primary Completion
2024-06-05
Completion
2024-06-05

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05287906 on ClinicalTrials.gov