Trial Outcomes & Findings for Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF) (NCT NCT05275920)

NCT ID: NCT05275920

Last Updated: 2024-10-09

Results Overview

Recruitment status

COMPLETED

Study phase

Target enrollment

2211 participants

Primary outcome timeframe

Through study completion, an average of 6 months

Results posted on

2024-10-09

Participant Flow

Participant milestones

Participant milestones
Measure	Best Practice Alert Group Providers will receive a BPA at the time of visit for patients with HFrEF who are not on MRA (and who do not have contraindication to MRA). This alert will display the patient's current HFrEF therapies, EF, blood pressure, potassium, and glomerular filtration rate. The alert will give access to an outpatient heart failure order set, and also provide links to the most recent guidelines. Best Practice Alert (BPA): A BPA will fire in the EHR reminding care providers of the best practice when prescribing medical therapies for heart failure patients.	In-Basket Message Group Providers will receive a monthly in-basket messages linking to a list of patients who have been seen in the past 2 months or will be seen in the upcoming month with HFrEF who are not on MRA (and who do not have contraindication to MRA). This list will display each patient's current hFrEF therapies, EF, blood pressure, potassium, glomerular filtration rate, date of last visit, and date of next visit. From the list, providers can access the patient's chart, order medications, and document communication with the patient. In-Basket Message: An In-Basket message will be sent biweekly to care providers with a reminder of the best practice when prescribing medical therapies for heart failure	Control Group Patients who will receive the current standard practice of care (no BPA or in-basket message)
Overall Study STARTED	755	812	644
Overall Study COMPLETED	755	812	644
Overall Study NOT COMPLETED	0	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF)

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Best Practice Alert Group n=755 Participants Providers will receive a BPA at the time of visit for patients with HFrEF who are not on MRA (and who do not have contraindication to MRA). This alert will display the patient's current HFrEF therapies, EF, blood pressure, potassium, and glomerular filtration rate. The alert will give access to an outpatient heart failure order set, and also provide links to the most recent guidelines. Best Practice Alert (BPA): A BPA will fire in the EHR reminding care providers of the best practice when prescribing medical therapies for heart failure patients.	In-Basket Message Group n=812 Participants Providers will receive a monthly in-basket messages linking to a list of patients who have been seen in the past 2 months or will be seen in the upcoming month with HFrEF who are not on MRA (and who do not have contraindication to MRA). This list will display each patient's current hFrEF therapies, EF, blood pressure, potassium, glomerular filtration rate, date of last visit, and date of next visit. From the list, providers can access the patient's chart, order medications, and document communication with the patient. In-Basket Message: An In-Basket message will be sent biweekly to care providers with a reminder of the best practice when prescribing medical therapies for heart failure	Control Group n=644 Participants Patients who will receive the current standard practice of care (no BPA or in-basket message)	Total n=2211 Participants Total of all reporting groups
Age, Continuous	73.0 years n=99 Participants	73.0 years n=107 Participants	74.0 years n=206 Participants	73.0 years n=7 Participants
Sex: Female, Male Female	220 Participants n=99 Participants	209 Participants n=107 Participants	204 Participants n=206 Participants	633 Participants n=7 Participants
Sex: Female, Male Male	535 Participants n=99 Participants	603 Participants n=107 Participants	440 Participants n=206 Participants	1578 Participants n=7 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	103 Participants n=99 Participants	82 Participants n=107 Participants	66 Participants n=206 Participants	251 Participants n=7 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	600 Participants n=99 Participants	668 Participants n=107 Participants	532 Participants n=206 Participants	1800 Participants n=7 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	52 Participants n=99 Participants	62 Participants n=107 Participants	46 Participants n=206 Participants	160 Participants n=7 Participants
Race (NIH/OMB) American Indian or Alaska Native	1 Participants n=99 Participants	0 Participants n=107 Participants	3 Participants n=206 Participants	4 Participants n=7 Participants
Race (NIH/OMB) Asian	28 Participants n=99 Participants	28 Participants n=107 Participants	27 Participants n=206 Participants	83 Participants n=7 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	2 Participants n=99 Participants	0 Participants n=107 Participants	2 Participants n=206 Participants	4 Participants n=7 Participants
Race (NIH/OMB) Black or African American	78 Participants n=99 Participants	57 Participants n=107 Participants	56 Participants n=206 Participants	191 Participants n=7 Participants
Race (NIH/OMB) White	490 Participants n=99 Participants	586 Participants n=107 Participants	448 Participants n=206 Participants	1524 Participants n=7 Participants
Race (NIH/OMB) More than one race	75 Participants n=99 Participants	75 Participants n=107 Participants	46 Participants n=206 Participants	196 Participants n=7 Participants
Race (NIH/OMB) Unknown or Not Reported	81 Participants n=99 Participants	66 Participants n=107 Participants	62 Participants n=206 Participants	209 Participants n=7 Participants
Region of Enrollment United States	755 participants n=99 Participants	812 participants n=107 Participants	644 participants n=206 Participants	2211 participants n=7 Participants

PRIMARY outcome

Timeframe: Through study completion, an average of 6 months

Outcome measures

Outcome measures
Measure	Best Practice Alert Group n=755 Participants Providers will receive a BPA at the time of visit for patients with HFrEF who are not on MRA (and who do not have contraindication to MRA). This alert will display the patient's current HFrEF therapies, EF, blood pressure, potassium, and glomerular filtration rate. The alert will give access to an outpatient heart failure order set, and also provide links to the most recent guidelines. Best Practice Alert (BPA): A BPA will fire in the EHR reminding care providers of the best practice when prescribing medical therapies for heart failure patients.	In-Basket Message Group n=812 Participants Providers will receive a monthly in-basket messages linking to a list of patients who have been seen in the past 2 months or will be seen in the upcoming month with HFrEF who are not on MRA (and who do not have contraindication to MRA). This list will display each patient's current hFrEF therapies, EF, blood pressure, potassium, glomerular filtration rate, date of last visit, and date of next visit. From the list, providers can access the patient's chart, order medications, and document communication with the patient. In-Basket Message: An In-Basket message will be sent biweekly to care providers with a reminder of the best practice when prescribing medical therapies for heart failure	Control Group n=644 Participants Patients who will receive the current standard practice of care (no BPA or in-basket message)
Number of Participants Prescribed Mineralocorticoid Receptor Antagonists (MRA) During Study	224 Participants	127 Participants	75 Participants

SECONDARY outcome

Timeframe: Through study completion, an average of 6 months