Trial Outcomes & Findings for Evaluating the Feasibility of VR for Pediatric Renal Biopsies (NCT NCT05267704)

NCT ID: NCT05267704

Last Updated: 2026-03-12

Results Overview

Acceptability of VR as non-pharmacologic sedation was assessed based on a team-made Likert scale survey given to patients and parents (Likert scale, with 1 = "strongly disagree" as most dissatisfied with VR experience and 5 = "strongly agree" as most satisfied with VR experience and a better perceived outcome

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

32 participants

Primary outcome timeframe

From arrival to procedural room to completion of procedure (~30 minutes)

Results posted on

2026-03-12

Participant Flow

Pediatric patients aged 5 to 17 years were the enrolled participants, as they were the only individuals who engaged with the virtual reality (VR) environment during renal biopsies. Caregivers provided informed consent for their child's participation, and assent was obtained from the child when appropriate. Caregivers and sedation providers completed brief surveys about their perceptions of the VR experience but were not themselves enrolled in the study.

Participant milestones

Participant milestones
Measure
VR Arm
Pediatric patients age 5-17 using the VR headset during renal biopsy. Samsung Gear Virtual Reality Headset: VR headset displaying preselected game during renal biopsy
Overall Study
STARTED
32
Overall Study
COMPLETED
32
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
VR Arm
n=32 Participants
Pediatric patients age 5-17 using the VR headset during renal biopsy. Participants included 8 children aged 5-8, 15 children aged 9-12, and 9 children aged 13-17
Age, Categorical
<=18 years
32 Participants
n=32 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=32 Participants
Age, Categorical
>=65 years
0 Participants
n=32 Participants
Sex: Female, Male
Female
17 Participants
n=32 Participants
Sex: Female, Male
Male
15 Participants
n=32 Participants

PRIMARY outcome

Timeframe: From arrival to procedural room to completion of procedure (~30 minutes)

Acceptability of VR as non-pharmacologic sedation was assessed based on a team-made Likert scale survey given to patients and parents (Likert scale, with 1 = "strongly disagree" as most dissatisfied with VR experience and 5 = "strongly agree" as most satisfied with VR experience and a better perceived outcome

Outcome measures

Outcome measures
Measure
VR Arm
n=32 Participants
Pediatric patients age 5-17 using the VR headset during renal biopsy. Samsung Gear Virtual Reality Headset: VR headset displaying preselected game during renal biopsy
Number of Participants Who "Strongly Agreed" They Would Recommend VR to Others Undergoing Similar Procedures
Agree
0 participants (patients)
Number of Participants Who "Strongly Agreed" They Would Recommend VR to Others Undergoing Similar Procedures
Strongly Agree
32 participants (patients)

PRIMARY outcome

Timeframe: From arrival to procedural room to completion of procedure (~30 minutes)

Population: Acceptability of VR as non-pharmacologic sedation was assessed based on a team-made Likert scale survey given to patients and parents (Likert scale, with 1 = "strongly disagree" as most dissatisfied with VR experience and 5 = "strongly agree" as most satisfied with VR experience and a better perceived outcome

Acceptability of VR as non-pharmacologic sedation was assessed based on a team-made Likert scale survey given to patients and parents (Likert scale, with 1 = "strongly disagree" as most dissatisfied with VR experience and 5 = "strongly agree" as most satisfied with VR experience and a better perceived outcome

Outcome measures

Outcome measures
Measure
VR Arm
n=32 Participants
Pediatric patients age 5-17 using the VR headset during renal biopsy. Samsung Gear Virtual Reality Headset: VR headset displaying preselected game during renal biopsy
Number of Parents Who "Agreed" or "Strongly Agreed" They Would Recommend VR to Others Undergoing Similar Procedures
Agree
3 participants (parents)
Number of Parents Who "Agreed" or "Strongly Agreed" They Would Recommend VR to Others Undergoing Similar Procedures
Strongly Agree
29 participants (parents)

SECONDARY outcome

Timeframe: From arrival to procedural room to completion of procedure (~30 minutes)

Anxiety as recorded on the Childhood Anxiety Meter was assessed at the start of the procedure and after the procedure was completed with the VR experience. CAM is recorded on a 0-10 scale using an analogy of mercury thermometer to ask children to their rate level of anxiety, with a higher score indicating a greater level anxiety.

Outcome measures

Outcome measures
Measure
VR Arm
n=32 Participants
Pediatric patients age 5-17 using the VR headset during renal biopsy. Samsung Gear Virtual Reality Headset: VR headset displaying preselected game during renal biopsy
Mean Difference in Self-reported Procedural Anxiety (Change in Childhood Anxiety Meter)
3.47 score on a scale
Interval 2.47 to 4.46

SECONDARY outcome

Timeframe: From arrival to procedural room to completion of procedure (~30 minutes)

Anxiety as recorded on the Children's Fear Scale was assessed at the start of the procedure and after the procedure was completed with the VR experience. CFS is recorded on a 0-4 numeric scale, with 4 being the highest fear/anxiety related to the procedure.

Outcome measures

Outcome measures
Measure
VR Arm
n=32 Participants
Pediatric patients age 5-17 using the VR headset during renal biopsy. Samsung Gear Virtual Reality Headset: VR headset displaying preselected game during renal biopsy
Mean Difference in Self-reported Procedural Anxiety (Change in Child Fear Scale)
1.47 score on a scale
Interval 1.09 to 1.85

Adverse Events

VR Arm

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Omar Salman, MD

University of California, San Francisco

Phone: 6159733909

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place