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Earlier Diagnosis and Better Treatment Mission Related to the Cohort Programme

NCT05266872 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1800

Last updated 2025-08-06

No results posted yet for this study

Summary

The Luxembourg Parkinson's Study is an ongoing longitudinal nationwide monocentric observational study. It collects extensive clinical, molecular, genetic, and digital device-based longitudinal data, as well as foreseen post-mortem diagnostic validation (Hipp et al., 2018). The cohort consists of more than 1,600 participants from Luxembourg and the Greater Region, comprising patients with typical PD or atypical parkinsonism - irrespective of disease stage, age, cognitive status, comorbidities, or linguistic background - followed-up annually and age- and sex-matched healthy control subjects followed-up every 4 years. To provide a large, longitudinally followed, and deeply phenotyped set of patients and controls for clinical and fundamental research on PD, the investigators have implemented an open-source digital platform that has been partly harmonized with other international PD cohort studies. This effort is flanked by comprehensive biosampling efforts assuring high quality and sustained availability of body liquids and tissue biopsies (including blood, urine, stool, saliva, hair, skin biopsy and cerebrospinal fluid). All data and samples are stored, curated, and integrated into state-of-the-art data and biobank facilities.

Conditions

  • Parkinson Disease

Interventions

OTHER

Observational study with sample and data collection

Observational study with sample and data collection

Sponsors & Collaborators

  • University of Luxembourg

    collaborator OTHER

  • Laboratoire National de Santé (LNS)

    collaborator UNKNOWN

  • Centre Hospitalier du Luxembourg

    collaborator OTHER

  • Luxembourg Institute of Health

    lead OTHER_GOV

Principal Investigators

  • Rejko Rejko, Dr · Luxembourg Institute of Health

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-12-19
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Luxembourg

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05266872 on ClinicalTrials.gov