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Ganglionic Local Opioid Analgesia at the Ganglion Cervicale Superius

NCT05257655 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3

Last updated 2023-10-03

No results posted yet for this study

Summary

The blockade of the superior cervical ganglion (GCS) of the sympathetic trunk is a very special form of therapy. The transoral blocking technique, also known as GLOA (ganglionic local opioid analgesia), is very suitable for achieving GCS. A total of 5 μg of sufentanil in 2 ml of sodium chlorid are applied.

Since no imaging evidence of the injected substances has been published for a GLOA in a living person, it is planned to carry out an MRI examination immediately after the ganglionic local opioid analgesia in order to show the spread and distribution pattern of the injected substance. It is also planed to show a correlation of the spread of the injected substance with the efficacy of the intervention.

To determine the interrater reliability, the GLOA is carried out alternately by 2 different examiners and the existing MRI images of the GLOA are assessed by an radiologist and anatomist in a blinded manner.

In a follow-up after 1 and 3 months, the questionnaires and pain scores are evaluated again.

Conditions

  • Trigeminal Neuralgia, Idiopathic
  • Postherpetic; Neuralgia, Trigeminal (Etiology)
  • Glossopharyngeal Neuralgia
  • Atypical Facial Pain

Interventions

PROCEDURE

MRI after ganglionic local opioid analgesia (GLOA)

MRI after Ganglionic Local Opioid Analgesia at the Ganglion Cervicale Superius

Sponsors & Collaborators

  • University of Klagenfurt

    collaborator OTHER

  • Klinikum Klagenfurt am Wörthersee

    lead OTHER

Principal Investigators

  • Rudolf Likar, Prof. · Klinikum Klagenfurt am Wörthersee

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-09
Primary Completion
2023-08-31
Completion
2023-10-01

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05257655 on ClinicalTrials.gov