Triple Antigen vs Monoantigen Immunotherapy for Warts
NCT05254561 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 160
Last updated 2022-02-24
Summary
Warts can be resistant to treatment or return despite the use of many therapeutic modalities. Combining immunotherapy might contribute to better response rates, particularly in recalcitrant warts, which is a real therapeutic challenge. The purpose of this study was to assess the effectiveness and safety of a triple intralesional immunotherapy combination composed of PPD, Candida antigen and MMR versus either agent alone in the management of multiple recalcitrant warts.
Conditions
- Triple Intralesional Immunotherapy Combination in Multiple Recalcitrant Warts
Interventions
- BIOLOGICAL
-
Intralesional antigen immunotherapy
Randomized double-blinded comparative effectiveness and safety clinical trial
Sponsors & Collaborators
-
Zagazig University
lead OTHER_GOV
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 10 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-20
- Primary Completion
- 2021-06-20
- Completion
- 2021-11-15
Countries
- Egypt
Study Locations
More Related Trials
-
Comparison Between Intralesional Injection of Plasma Rich Platelets and Candida Antigen in Plane Warts
NCT05652998 ·Status: UNKNOWN ·Phase: PHASE4
-
Interleukin 4 and Interferon Gamma Predictors of Human Papillomavirus Immunotherapy in Warts
NCT05100043 ·Status: COMPLETED
-
Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts
NCT03158168 ·Status: UNKNOWN ·Phase: PHASE3
-
Sclerotherapy and Candida Antigen in Treatment of Common Warts
NCT06749665 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study With a Topical Gel to Treat Common Warts in Adults
NCT00117871 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Efficacy of Cryotherapy Combined With Intralesional Hepatitis B Virus Vaccine Versus Either Therapy in the Treatment of Multiple Cutaneous Warts :a Comparative Study
NCT05902624 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts
NCT06691542 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Intralesional Injection of Acyclovir Versus Candida Antigen in Treatment of Plantar Warts
NCT05429151 ·Status: UNKNOWN ·Phase: PHASE4
-
Complement Component 3c and Tumor Necrosis Factor-α in Patients With Human Papillomavirus-Induced Cutaneous Warts
NCT04399577 ·Status: COMPLETED ·Phase: PHASE2
-
Study With a Topical Gel to Treat Common Warts in Adults
NCT00117923 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Therapy of Imiquimod 5%Cream and Cryotherapy vs Monotherapy for Common Warts:Randomized Comparative Trial.
NCT06973473 ·Status: NOT_YET_RECRUITING
-
Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients
NCT03153566 ·Status: UNKNOWN ·Phase: PHASE3
-
Intralesional Vitamin D3 Versus Intralesional Acyclovir in Treatment of Plantar Warts
NCT05324904 ·Status: UNKNOWN ·Phase: NA
-
A Cohort Study of Hyperthermia and Imiquimod for the Treatment of Flat Warts
NCT05146895 ·Status: UNKNOWN ·Phase: NA
-
Combination Therapy for Warts: Candida Antigen vs. Topical Keratolytic
NCT07329907 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Imiquimod Cream Prior to Ablative Therapy in External Ano-Genital Warts
NCT00189293 ·Status: COMPLETED ·Phase: PHASE4
-
The Efficacy of Intra-lesional Bleomycin Versus Intra-lesional Purified Protein Derivative in Treatment of Palmoplantar Warts
NCT03477448 ·Status: UNKNOWN ·Phase: PHASE4
-
Four Week Safety and Efficacy Study With a Topical Gel to Treat Common Warts in Adults
NCT00115141 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of Squamous Cell Carcinoma antigen2 in Verruca Vulgaris
NCT05409365 ·Status: UNKNOWN
-
Gardasil Versus Cervarix in the Treatment of Warts
NCT05383625 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Recalcitrant Hand and Foot Warts With Intense Pulsed Light - a Randomized Controlled Trial
NCT00254280 ·Status: UNKNOWN ·Phase: NA
-
Human Papillomavirus (HPV) Vaccination vs. Placebo for the Treatment of Refractory Cutaneous Warts
NCT05625633 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Immunotherapy in Eyelid Viral Papilloma
NCT06720467 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Intralesional MMR Vaccine,Intralesional Candidal Antigen&Topical Podophyllin in Treatment of Genital Warts
NCT03853785 ·Status: UNKNOWN ·Phase: PHASE3
-
Intralesional Acyclovir Versus Cryotherapy in the Treatment of Plantar Warts. A Randomized Controlled Trial.
NCT06261684 ·Status: RECRUITING ·Phase: PHASE2/PHASE3