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English Mammography Screening Outcomes by Age, Frequency and Test Threshold

NCT05247463 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 10000000

Last updated 2023-12-12

No results posted yet for this study

Summary

Breast cancer screening involves taking mammograms (x-rays) of women's breasts to search for signs of cancer. This study investigates the impact of test threshold, screening interval (frequency) and age of eligibility on intermediate outcomes, and health outcomes such as mortality and morbidity. This observational study links breast cancer screening, cancer registry and mortality registration data to answer these questions.

Conditions

Interventions

OTHER

Increase in upper age of eligibility for breast cancer screening from 64 to 70

The upper age limit of eligibility for Breast Cancer Screening increased in England from 64 to 70 as a result of the NHS Cancer Plan, so women were offered an additional 2 rounds of screening.

OTHER

Screening round length

The target round length (frequency) of breast cancer screening in England is every 3 years. However in practice there is variability in this due to local centre capacity. The exposures are round lengths of approximately 2 years and approximately 3 years

DIAGNOSTIC_TEST

Screening test threshold

Radiologists and equivalent health professionals examine women's screening mammograms for potential signs of cancer, and recall some women for further diagnostic tests. Each has a different test threshold for recall, characterised by the proportion of previous cases that they have recalled.

Sponsors & Collaborators

  • University of Birmingham

    collaborator OTHER

  • University of Bristol

    collaborator OTHER

  • University of Warwick

    lead OTHER

Eligibility

Min Age
47 Years
Max Age
73 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2024-12-30
Completion
2024-12-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05247463 on ClinicalTrials.gov