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Lidocaine VS Hemodynamic, Metabolic and Hormonal Response

NCT05238506 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 132

Last updated 2023-10-31

No results posted yet for this study

Summary

Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management in adults. In children population promising but limited evidence is available. The study has been planned to evaluate the efficacy of continuous intravenous infusion of lidocaine in alleviation of hemodynamic reaction to tracheal intubation, as well as metabolic and hormonal response to laparoscopic procedure in children.

Conditions

  • Hemodynamic Response
  • Acute Appendicitis
  • Complication of Treatment
  • Opioid Consumption
  • Pneumoperitoneum

Interventions

DRUG

Intravenous lidocaine

Intraoperative intravenous lidocaine infusion.

DRUG

Normal saline infusion

Intraoperative intravenous normal saline infusion.

Sponsors & Collaborators

  • Medical University of Warsaw

    lead OTHER

Principal Investigators

  • Maciej Kaszyński · Medical University of Warsaw

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Months
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-12
Primary Completion
2023-08-08
Completion
2023-08-08

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05238506 on ClinicalTrials.gov