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Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate

NCT05231980 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2023-07-20

No results posted yet for this study

Summary

This study evaluate the addition of PTX and ALA to clomiphene citrate in the treatment of polycystic ovary.

Conditions

  • Clomiphene Citrate
  • Resistant Ovary Syndrome
  • Polycystic Ovary Syndrome

Interventions

DIETARY_SUPPLEMENT

Alpha lipoic acid (ALA)

ALA is sold as a dietary supplement, either by itself or incorporated into a multivitamin product. it also has anti-oxidant effect.

DRUG

Pentoxifylline (PTX)

Pentoxifylline is a methylxanthine derivative which acts as a vasodilator by increasing blood flow to tissues, inhibits inflammatory responses, and reduces blood viscosity by impeding platelet aggregation

DRUG

Clomiphene Citrate

is a medication used to treat infertility in women who do not ovulate

Sponsors & Collaborators

  • Misr University for Science and Technology

    collaborator OTHER

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Nagwa Al Sabri, Phd · Ainshams university

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
39 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-05
Primary Completion
2023-05-06
Completion
2023-06-07

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05231980 on ClinicalTrials.gov