MedTrace Logo

Electrical and Mechanical Activation in PAcing The His Bundle Conduction sYstem

NCT05222672 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2022-11-30

No results posted yet for this study

Summary

In recent years, the finding of long-term deleterious effects of right ventricular pacing (RVP) has led to an ongoing search for alternative pacing sites such as His bundle stimulation. The depolarization of the ventricles through the His-Purkinje cardiac conduction system seems to represent an ideal physiological approach to ventricular pacing, capable of engaging the normal conduction pathways and determining synchronous ventricular activation. However, there are still no clinical studies that have evaluated the electromechanical functions of the left ventricle with His bundle pacing (HBP) identified after electroanatomical reconstruction with 3D mapping system. Investigators aimed to compare the electromechanical effects on left ventricle of HBP, compared to RVP stimulation and to spontaneous rhythm of each patient.

Conditions

  • Pacemaker DDD
  • His Bundle Pacing
  • Right Ventricular Pacing

Interventions

OTHER

His Bundle Pacing

Pacing of the His bundle

Sponsors & Collaborators

  • University Hospital of Ferrara

    lead OTHER

Principal Investigators

  • Matteo Bertini, MD, PhD · Università degli Studi di Ferrara

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-01
Primary Completion
2022-01-07
Completion
2022-01-07

Countries

  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05222672 on ClinicalTrials.gov