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General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia

NCT05210764 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 366

Last updated 2025-07-31

No results posted yet for this study

Summary

The change profiles of indices derived from pEEG such as phase-amplitude coupling and bicoherence based on individual general anesthetics in children have not been examined in previous literature. Whether those indices have the abilities to predict individual drug-related anesthesia depth in children need to be explored.

Conditions

  • General Anesthetic
  • Electroencephalogram

Interventions

DRUG

propofol

General anesthesia is induced and maintained mainly with propofol.

DRUG

sevoflurane

General anesthesia is induced and maintained mainly with sevoflurane.

DRUG

S-ketamine

General anesthesia is induced mainly with S-ketamine and maintained mainly with propofol.

Sponsors & Collaborators

  • Peking University First Hospital

    lead OTHER

Principal Investigators

  • Dong-Xin Wang, MD, PhD · Peking University First Hospital

Eligibility

Min Age
1 Minute
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-01
Primary Completion
2026-03-31
Completion
2026-08-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05210764 on ClinicalTrials.gov