Envafolimab Combined With Endostar in the First-line Treatment of Advanced NSCLC
NCT05203276 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2023-06-22
Summary
To evaluate the efficacy and safety of envafolimab combined with endostar in the first-line treatment of advanced Non-small Cell Lung Cancer With PD-L1 positive expression
Conditions
- Lung Neoplasms
Interventions
- DRUG
-
Envafolimab
300mg,SC,Q3W,d1
- DRUG
-
Endostar
210mg,CIV,Q3W,d1-3
Sponsors & Collaborators
-
The First People's Hospital of Lianyungang
lead OTHER
Principal Investigators
-
Xiaodong Jiang, Doc · The First People's Hospital of Lianyungang
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-03-01
- Primary Completion
- 2024-05-30
- Completion
- 2024-06-30
Countries
- China
Study Locations
More Related Trials
-
Endostar/PD-1 Inhibitors Combined With PP for Advanced NSCLC
NCT04063449 ·Status: UNKNOWN ·Phase: NA
-
A Study of Endostar Combined With Chemotherapy and Immunotherapy in Lung Squamous Cell Carcinom
NCT05782764 ·Status: UNKNOWN ·Phase: PHASE4
-
Recombinant Human Endostatin Combined With Envafolimab and Synchronal Radiochemotherapy
NCT06279754 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Envafolimab Plus Docetaxel In Combination With or Without Trilaciclib Versus Docetaxel in Advanced NSCLC
NCT05910034 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study of Endostar Combined With Chemotherapy Followed by Endostar Maintenance Therapy to Treat Advanced Non-small Cell Lung Cancer (NSCLC)
NCT01028729 ·Status: UNKNOWN ·Phase: PHASE4
-
PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer
NCT06429696 ·Status: RECRUITING ·Phase: PHASE2
-
Concurrent Endostar, Paclitaxel/Carboplatin and Radiotherapy for Locally Advanced Non-small Cell Lung (RT0902)
NCT01158144 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin
NCT06698965 ·Status: RECRUITING ·Phase: PHASE2
-
Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy and Sequential Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer
NCT07349225 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Second-line Therapy Study of Combined Chemotherapy and Endostar to Patients With Non-Small Cell Lung Cancer(NSCLC)
NCT00813332 ·Status: UNKNOWN ·Phase: PHASE4
-
Pembrolizumab as First-line Treatment for Advanced NSCLC Complicated With COPD
NCT05578222 ·Status: UNKNOWN ·Phase: PHASE2
-
Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC.
NCT05068427 ·Status: COMPLETED ·Phase: PHASE2
-
Endostar Continued Pumping Into Vein Combining With Gemcitabine-Carboplatin to Treat Non-Small Cell Lung Cancer (NSCLC)
NCT01549093 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Endostatin Combined With Docetaxel in the Treatment of Advanced Non-small Cell Lung Cancer Patients
NCT01192230 ·Status: UNKNOWN ·Phase: PHASE2
-
Pamiparib for Consolidation Treatment of Unprogressed LS-SCLC After Concurrent Chemoradiotherapy
NCT05483543 ·Status: UNKNOWN ·Phase: PHASE2
-
Anlotinib Combined With Nivolumab for Non-Small Cell Lung Cancer
NCT04211896 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Pembrolizumab and Single Agent Chemotherapy as First Line Treatment for Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer With Eastern Cooperative Oncology Group (ECOG) Performance Status of 2
NCT04297605 ·Status: RECRUITING ·Phase: PHASE1
-
Durvalumab Combined With Chemotherapy and Stereotactic Body Radiotherapy (SBRT) in Patients With Oligometastatic Non-small Cell Lung Cancer (NSCLC)
NCT04255836 ·Status: UNKNOWN ·Phase: PHASE2
-
Preconditioning Chemotherapy Combination With Cytokine Induced Killer Cell (CIK) Immunotherapy
NCT01902875 ·Status: UNKNOWN
-
Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC
NCT06123754 ·Status: RECRUITING ·Phase: PHASE3
-
Pegylated Liposomal Doxorubicin and Carboplatin as First Line Treatment for Patients With Advanced Non-small Cell Lung Cancer
NCT01051362 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study Evaluating the Efficacy of PD-1 Inhibitor Combined With Denosumab and Chemotherapy in Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Patients With Driver Gene-Negative Status
NCT07034391 ·Status: RECRUITING ·Phase: PHASE2
-
Treatment of Non-small Cell Lung Cancer With Cytokine-induced Killer (CIK) Cells Blocked by PD-1 Antibody
NCT03282435 ·Status: UNKNOWN ·Phase: PHASE1
-
A Exploratory Study of Nivolumab Monotherapy or in Combination With Nab-paclitaxel and Carboplatin in Early Stage NSCLC in China
NCT04015778 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
PD-1 Inhibitors Consolidation in Extensive-stage Small Cell Lung Cancer
NCT03971214 ·Status: UNKNOWN ·Phase: PHASE1