Trial Outcomes & Findings for Study of a Behavioral Intervention for Older Advanced Cancer Patients and Their Caregivers (NCT NCT05200572)
NCT ID: NCT05200572
Last Updated: 2025-11-25
Results Overview
The number of participants that complete the entire study procedures out of the number of participants enrolled in the study. The study consisted of one patient and one caregiver (defined as a dyad) that completed the study procedures together), therefore there were 19 dyads enrolled in the study or 38 participants. The proportion of participants that completed the study was determined out of the 19 dyads enrolled.
COMPLETED
NA
38 participants
week 14
2025-11-25
Participant Flow
42 patients were approached for consent.
We approached 42 patients for consent. We enrolled 38 individual patients in the DLR Intervention study.
Participant milestones
| Measure |
DLR Intervention
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Overall Study
STARTED
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38
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Overall Study
COMPLETED
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24
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Overall Study
NOT COMPLETED
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14
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Reasons for withdrawal
| Measure |
DLR Intervention
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Overall Study
Withdrawal by Subject
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14
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Baseline Characteristics
Study of a Behavioral Intervention for Older Advanced Cancer Patients and Their Caregivers
Baseline characteristics by cohort
| Measure |
Dyadic Life Review Intervention (Patients and Caregivers)
n=38 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): Dyadic Life Review (DLR) was delivered to both members of each patient-caregiver dyad. Each dyad completed 8 video sessions facilitated by a licensed clinician. DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Age, Categorical
<=18 years
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0 Participants
n=9 Participants
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Age, Categorical
Between 18 and 65 years
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2 Participants
n=9 Participants
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Age, Categorical
>=65 years
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36 Participants
n=9 Participants
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Sex: Female, Male
Female
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22 Participants
n=9 Participants
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Sex: Female, Male
Male
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16 Participants
n=9 Participants
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Ethnicity (NIH/OMB)
Hispanic or Latino
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0 Participants
n=9 Participants
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Ethnicity (NIH/OMB)
Not Hispanic or Latino
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33 Participants
n=9 Participants
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Ethnicity (NIH/OMB)
Unknown or Not Reported
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5 Participants
n=9 Participants
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Race (NIH/OMB)
American Indian or Alaska Native
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0 Participants
n=9 Participants
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Race (NIH/OMB)
Asian
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0 Participants
n=9 Participants
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Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
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0 Participants
n=9 Participants
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Race (NIH/OMB)
Black or African American
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2 Participants
n=9 Participants
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Race (NIH/OMB)
White
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32 Participants
n=9 Participants
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Race (NIH/OMB)
More than one race
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0 Participants
n=9 Participants
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Race (NIH/OMB)
Unknown or Not Reported
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4 Participants
n=9 Participants
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Region of Enrollment
United States
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38 participants
n=9 Participants
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PRIMARY outcome
Timeframe: week 14The number of participants that complete the entire study procedures out of the number of participants enrolled in the study. The study consisted of one patient and one caregiver (defined as a dyad) that completed the study procedures together), therefore there were 19 dyads enrolled in the study or 38 participants. The proportion of participants that completed the study was determined out of the 19 dyads enrolled.
Outcome measures
| Measure |
Cancer Patients
n=19 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Proportion of Dyads That Complete the Study
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12 Dyads
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PRIMARY outcome
Timeframe: BaselinePopulation: Includes all participants approached for study enrollment (N=38).
The number of participants who consented for the study out of the number of eligible participants who were approached and asked if they would like to be in the study. This outcome measures the proportion of potential participants approached who provided informed consent to participate in the Dyadic Life Review (DLR) study. A total of 42 patients were approached, and 38 provided informed consent to participate.The proportion was calculated as the number who consented divided by the total number approached (38 ÷ 42 × 100 = 90.5 percent).
Outcome measures
| Measure |
Cancer Patients
n=42 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Proportion of Participants That Consent Who Are Approached for the Study
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38 Participants
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PRIMARY outcome
Timeframe: week 14Population: Includes all participants who completed the intervention and participated in the qualitative interview. Only 12 out of 38 participants completed the interview.
The proportion of participants who completed the full study intervention and indicated that the intervention was acceptable during post-intervention qualitative interviews. Acceptability was assessed only among participants who completed all study sessions.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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Number of Participants Who State the Intervention is Acceptable During a Qualitative Interview
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12 Participants
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SECONDARY outcome
Timeframe: baseline to week 14Population: Includes 12 caregivers who completed both baseline and week 14 assessments. Data from patient participants were not collected for this outcome.
UCLA Loneliness Scale assesses perceived loneliness on a 0-10 scale, with higher scores indicating greater loneliness. Mean change was calculated as week 14 score minus baseline score for caregivers who completed the measure.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in the UCLA Loneliness Score for Caregivers
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0.64 score on a scale
Standard Deviation 4.97
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both assessments (N=12). Patients were not assessed for this measure.
This measures the quality of the relationship with the care-receiver: assesses quality of relationship between participant and family member and has demonstrated valid scores across several relationship types, including spouses and other family members. The scale of this instrument ranges from 1 to 7 with higher scores indicating more closeness. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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Mean Change in Unidimensional Relationship Closeness Scale for Caregivers
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-0.05 score on a scale
Standard Deviation 0.7
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both assessments (N=12). Patients were not assessed for this measure.
Measures perceived stress, scale 0-40, higher scores indicate greater stress. Mean change calculated as week 14 minus baseline for caregivers who completed the measure.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in Perceived Stress Scale for Caregivers
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-0.17 score on a scale
Standard Deviation 2.08
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both assessments (N=12). Data from patients were not collected.
Items assess both positive and negative aspects of caregiving. Subscales: role captivity, overload, relational deprivation, competence, personal gain, family beliefs, family conflict, job conflict. The scale ranges from 0 to 24 with higher scores indicating a more negative caregiver experience. Preliminary evidence for the validity and reliability of the Caregiver Reaction Scale. Mean change calculated as week 14 minus baseline for caregivers who completed the measure.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in Caregiver Reaction Scale for Caregivers
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-0.42 score on a scale
Standard Deviation 2.07
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both assessments (N=12). Patients were not assessed.
The purpose of this scale is to identify the clinical threshold of depression in older adults. The scale ranges from 0 to 15 with higher scores indicating worse depression. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated. Mean change calculated as week 14 minus baseline for caregivers who completed the measure.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in Geriatric Depression Scale for Caregivers
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1.33 score on a scale
Standard Deviation 2.53
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both assessments (N=12). Patients were not assessed for this measure.
This tool is a 10-point self-report measure to capture distress and identify a list of sources of that distress. The scale ranges from 0-10 with higher scores indicating more distress. Mean change calculated as week 14 minus baseline for caregivers who completed the measure.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in Distress Thermometer and Problem List for Caregivers
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-0.42 score on a scale
Standard Deviation 2.43
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both assessments (N=12). Patients were not assessed.
This is a 7-item measure to assess relationship quality that ranges from 0-36 with higher scores indicating positive relationship quality. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in Dyadic Adjustment Scale-7 for Caregivers
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1.17 score on a scale
Standard Deviation 3.93
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SECONDARY outcome
Timeframe: baseline to week 14Population: Overall Number of Participants Analyzed (N=12) reflects caregiver participants only; data were not collected from patient participants for this outcome.
18-item measure assessing perceived received and provided support. Scale 0-145, higher scores indicate better dyadic coping. Mean change calculated as week 14 minus baseline for caregivers who completed the measure.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in Dyadic Support Questionnaire For Caregivers
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1.83 change in score pre to post intervention
Standard Deviation 6.56
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SECONDARY outcome
Timeframe: baseline to week 14Population: 11 patient-caregiver dyads with complete data (N=22 participants). We analyzed 11 patient distress scores and 11 caregiver distress scores to determine the mean change in the correlation between the patient and caregiver distress scores. One subject did not complete the distress score of the 12 patient and caregiver dyads (24 total subjects) who completed the study, so we analyzed the 11 patients and 11 caregivers (22 subjects) for this outcome.
Distress measured using Distress Thermometer (0-10, higher = more distress). Pearson correlation coefficient between patient and caregiver distress scores calculated at baseline and week 14; mean change = week 14 minus baseline.
Outcome measures
| Measure |
Cancer Patients
n=22 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in the Correlation Between Patient and Caregiver Distress
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-0.64 change in correlation coefficient (r)
Standard Deviation 0.05
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both baseline and week 14 assessments (N=12).
Patient-Reported Outcomes Measurement Information System 29-item profile (PROMIS29) - Depression Domain. Scores range from 0-10, with higher scores indicating worse depression. Mean change was calculated as week 14 minus baseline. Mean change calculated as week 14 minus baseline for caregivers who completed both assessments.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in PROMIS29 Depression Domain For Caregivers
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-3.23 score on a scale
Standard Deviation 6.93
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both baseline and week 14 assessments (N=12).
PROMIS29 - Anxiety Domain. Scores range from 0-10, with higher scores indicating worse anxiety. Mean change calculated as week 14 minus baseline. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in PROMIS29 Anxiety Domain For Caregivers
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1.61 score on a scale
Standard Deviation 8.31
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both baseline and week 14 assessments for this domain (N=11). Participants with missing or incomplete data for this domain were not included in the analysis.
PROMIS29 - Physical Function Domain. Scores range from 0-10, with higher scores indicating worse physical function. Mean change calculated as week 14 minus baseline. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=11 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in PROMIS29 Physical Function Domain For Caregivers
|
-0.56 score on a scale
Standard Deviation 1.73
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both baseline and week 14 assessments for this domain (N=11). Participants with missing or incomplete data for this domain were not included in the analysis.
PROMIS29 - Pain Interference Domain. Scores range from 0-10, with higher scores indicating more pain interference. Mean change calculated as week 14 minus baseline. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=11 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in PROMIS29 Pain Interference Domain For Caregivers
|
-2.45 score on a scale
Standard Deviation 7.66
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both baseline and week 14 assessments (N=12).
PROMIS29 - Fatigue Domain. Scores range from 0-10, with higher scores indicating worse fatigue. Mean change calculated as week 14 minus baseline. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=12 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in PROMIS29 Fatigue Domain For Caregivers
|
-1.59 score on a scale
Standard Deviation 7.82
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both baseline and week 14 assessments for this domain (N=11). Participants with missing or incomplete data for this domain were not included in the analysis.
PROMIS29 - Sleep Disturbance Domain. Scores range from 0-10, with higher scores indicating worse sleep disturbance. Mean change calculated as week 14 minus baseline. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=11 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in PROMIS29 Sleep Disturbance Domain For Caregivers
|
0.28 score on a scale
Standard Deviation 10.55
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SECONDARY outcome
Timeframe: baseline to week 14Population: Caregivers who completed both baseline and week 14 assessments for this domain (N=11). Participants with missing or incomplete data for this domain were not included in the analysis.
PROMIS29 - Ability to Participate in Social Roles Domain. Scores range from 0-10, with higher scores indicating worse social role participation. Mean change calculated as week 14 minus baseline. The change in score pre and post intervention was determined by subtracting the post intervention score from the pre intervention score and the mean of the change scores was calculated.
Outcome measures
| Measure |
Cancer Patients
n=11 Participants
Dyadic Life Review will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes.
Dyadic Life Review (DLR): DLR will consist of 8 sessions delivered by a trained licensed clinician (i.e, the PI or other trained clinician) via video-conferencing in weekly sessions of 60 minutes. Each session will facilitate a recall of each phase of life: childhood, adolescence, young adulthood, mid-life, earlier later life, and later life. While together, the patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life.
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|---|---|
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Mean Change in PROMIS29 Ability to Participate in Social Roles Domain For Caregivers
|
-0.57 score on a scale
Standard Deviation 5.37
|
Adverse Events
Cancer Patients and Caregivers (Dyadic Life Review Group)
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place