Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!)
NCT05196087 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2025-07-02
Summary
Patients who have undergone curative treatment may be at risk of relapse. This study will collect, annotate, and sequence biospecimens (blood, stool, and tissue) from patients across different tumor types to detect molecular residual disease (MRD) before metastases become radiographically or clinically detectable. This will allow for early cancer interception, and hopefully prolong relapse-free survival across tumor types.
Conditions
- Breast Cancer
- Melanoma
- Gastrointestinal Neuroendocrine Tumor
Sponsors & Collaborators
-
Princess Margaret Hospital, Canada
collaborator OTHER -
University Health Network, Toronto
lead OTHER
Principal Investigators
-
Lillian Siu, MD · Princess Margaret Hospital, Canada
-
Philippe Bedard, MD · Princess Margaret Hospital, Canada
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-20
- Primary Completion
- 2027-06-30
- Completion
- 2027-06-30
Countries
- Canada
Study Locations
More Related Trials
-
Tumor-Targeted-NIR-II Fluorescent Molecular Probes for the Identification of Breast Cancer Tissue and SLN Metastatic Status
NCT06713161 ·Status: RECRUITING
-
Radiomic Analysis for Predicting Treatment Response and Clinical Outcomes in Malignancies
NCT05170087 ·Status: UNKNOWN
-
HERPET- A Novel PET Imaging Study of HER2 in Breast Cancer
NCT03827317 ·Status: RECRUITING ·Phase: NA
-
Ultrasound Imaging, Spectroscopy and Ultrasound Imaging of Vascular Blood Flow as Early Indicators of Breast Cancer Response to Neoadjuvant Treatment.
NCT00437879 ·Status: RECRUITING
-
Tracking Triple-negative Breast Cancer Evolution Through Therapy
NCT03077776 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Development of Artificial Intelligence System for Detection and Diagnosis of Breast Lesion Using Mammography
NCT03708978 ·Status: COMPLETED
-
Comparison of Digital Breast Tomosynthesis to Conventional Mammography
NCT03442478 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Prognostic Monitoring for Women Who Have Completed Standard Treatment for Breast Cancer
NCT04145960 ·Status: UNKNOWN
-
Trial Comparing Radioactive Seed Localization to Standard Procedure for Non-palpable Breast Cancers
NCT00225927 ·Status: COMPLETED ·Phase: NA
-
Three-Dimensional Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
NCT06175078 ·Status: NOT_YET_RECRUITING
-
BIG Molecular Screening Feasibility Study
NCT02094742 ·Status: COMPLETED ·Phase: NA
-
NEPA in Patients With HER2-positive or HER2-low Advanced Breast Cancer Treated With T-DXd
NCT07132749 ·Status: ENROLLING_BY_INVITATION
-
Evaluation of the Potential Impact of an Artificial Intelligence Solution in Second Reading of Organized Screening.
NCT06479772 ·Status: COMPLETED
-
Study of Screening Brain MRIs in Stage IV Breast Cancer
NCT05115474 ·Status: RECRUITING ·Phase: PHASE2
-
Using of Costimulatory and co Inhibatory Immune Checkpoints as Diagnostic and Prognostic in Breast Cancer
NCT06169007 ·Status: NOT_YET_RECRUITING
-
Prospective Evaluation of AI R&D Tool for Patient Stratification - MoA Evaluation in Triple Negative Breast Cancer (PEAR-MET)
NCT06182306 ·Status: RECRUITING
-
New Technique as an Additional Diagnostic Tool for Women Undergoing Neoadjuvant Therapy for Breast Cancer
NCT00566085 ·Status: COMPLETED ·Phase: NA
-
Three-Dimensional Ultrasound and Spectroscopy as Early Indicators of Breast Cancer Response to Neoadjuvant Treatment
NCT06193122 ·Status: NOT_YET_RECRUITING
-
Infrared Imaging (Breast Scan IR) for Early Breast Cancer Detection
NCT00195026 ·Status: COMPLETED
-
Community Hospital Identification of High CV Risk Patients During Cancer Treatment
NCT02566109 ·Status: TERMINATED ·Phase: NA
-
Reoperation Rate in Breast-Conserving Surgery Using Confocal Histolog® Scanner for Intraoperative Margin Assessment
NCT05946759 ·Status: COMPLETED ·Phase: NA
-
AI-based pCR Assessment/Prediction in HER2-Positive BC Using PET/MRI
NCT06708910 ·Status: RECRUITING
-
The Added Value of DBT Over Mammography in Local Tumor Staging in Patients With BIRADS 4 or 5 Lesions
NCT06854887 ·Status: NOT_YET_RECRUITING
-
Development of a Horizontal Data Integration Classifier for Noninvasive Early Diagnosis of Breast Cancer
NCT04781062 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Prognostic Monitoring for Breast Cancer Patients With Recurrence and Metastasis After Surgery
NCT04145973 ·Status: UNKNOWN