Predicitve Value of Copeptin In CO-intoxicated Patients - A Prospective Cohort Study
NCT05193812 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2022-03-22
Summary
ALCOPOP is a prospective cohort study entitled "Predicitve Value of Copeptin in CO-intoxicated Patients". The primary objective of this study is to assess the independent association between early Copeptin and / or Troponin concentrations at presentation at the emergency department with disability-free survival after carbon monoxide (CO) -intoxication. Further secondary aims are to determine the independent association between early postoperative Copeptin and / or Troponin concentrations and major adverse cardiovascular events (MACE), mortality and long-term neurological outcome.
Adult patients with acute CO-intoxication (CO-hemoglobin \>10%) will be included. Main exposure will be Copeptin and Troponin concentrations. Primary endpoint will be disability-free survival at 90 days. The investigators assume to include 120 patients in 24 months
Conditions
- CO Poisoning
Sponsors & Collaborators
-
Heinrich-Heine University, Duesseldorf
lead OTHER
Principal Investigators
-
PD Stephan Sixt · Department of Anaesthesiology, University Hospital Duesseldorf
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-04-30
- Primary Completion
- 2024-05-31
- Completion
- 2024-05-31
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