MedTrace Logo

Documentation of Efficacy of Intralymphatic Allergen Immunotherapy

NCT05191186 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 450

Last updated 2025-08-12

No results posted yet for this study

Summary

Investigation of the clinical efficacy of 3 intralymphatic injections with grass pollen extract into inguinal lymph nodes on combined symptom-medication scores during grass pollen season in grass pollen allergic patients compared to placebo

Conditions

  • Allergic Rhinitis Due to Grass Pollen
  • Allergic Conjunctivitis of Both Eyes
  • Allergic Asthma

Interventions

DRUG

Grass pollen extract - Alutard Phleum pratense, ALK

injection in lymph node

Sponsors & Collaborators

  • University of Aarhus

    collaborator OTHER

  • University Hospital, Linkoeping

    collaborator OTHER

  • Aarhus University Hospital

    lead OTHER

Principal Investigators

  • Johannes M Schmid, MD PhD · Aarhus University Hospital/Aarhus University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-01
Primary Completion
2023-08-01
Completion
2023-12-31

Countries

  • Denmark
  • Sweden

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05191186 on ClinicalTrials.gov