Tyrosine Allergoid Paediatric and Adult Study
NCT05186025 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 320
Last updated 2026-01-30
Summary
The primary objective of this 5-year study is to demonstrate non-inferiority of children compared to adults by exploring long-term effectiveness after treatment with TA Bäume (trees) and TA Gräser (grass) following a perennial posology.
Conditions
- Allergic Rhinitis Due to Pollen
- Allergic Conjunctivitis
- Allergic Asthma
Interventions
- DRUG
-
MATA trees or MATA grass
Glutaraldehyde-modified and MCT® (MicroCrystalline Tyrosine)-adsorbed allergoids
Sponsors & Collaborators
-
Bencard Allergie GmbH
collaborator OTHER -
Allergy Therapeutics
lead INDUSTRY
Principal Investigators
-
Ralph Moesges, Prof. · ClinCompetence Cologne GmbH
Eligibility
- Min Age
- 5 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-06
- Primary Completion
- 2026-06-30
- Completion
- 2026-10-31
Countries
- Germany
Study Locations
More Related Trials
-
Evaluation of Safety and Efficacy of Specific Immunotherapy With Recombinant Major Allergens of Timothy Grass Pollen Adsorbed Onto Aluminium-hydroxide in Patients With IgE-mediated Allergic Rhinoconjunctivitis +/- Controlled Asthma
NCT00671268 ·Status: COMPLETED ·Phase: PHASE3
-
Induction of Immunogenicity With Different Doses of Grass MATA in Subjects Allergic to Grass and Rye Pollen
NCT00104377 ·Status: COMPLETED ·Phase: PHASE2
-
Different Doses of Tyrosine Adsorbed Grass Pollen Allergoid With Monophosphoryl Lipid A (MPL) in Patients Sensitized to Grass Pollen
NCT00133159 ·Status: COMPLETED ·Phase: PHASE2
-
Investigation of Safety+Efficacy of Different Doses of RagweedMATAMPL;Assessment of Residual Allergenicity Using Skin Prick Test
NCT00258635 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of Residual Allergenicity of Ragweed Pollen Allergoid With Monophosphoryl Lipid A (MPL) Using Skin Prick Testing
NCT00116285 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Recombinant Grass Pollen Allergen Cocktail in the Treatment of Allergic Rhinoconjunctivitis
NCT00309036 ·Status: COMPLETED ·Phase: PHASE3
-
App Based Study on the Symptoms of Patients With Allergic Rhinitis in the Pollen Season
NCT03112252 ·Status: COMPLETED
-
A Study in Children and Adolescents With Birch Pollen-induced Rhinoconjunctivitis
NCT04878354 ·Status: COMPLETED ·Phase: PHASE3
-
The Effects of Phenylephrine Compared With Those of Placebo and Pseudoephedrine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis (SAR)(P04579)
NCT00276016 ·Status: COMPLETED ·Phase: PHASE3
-
Hypothalamic-Pituitary-Adrenal (HPA)-Axis Study in Pediatric Subjects With Perennial Allergic Rhinitis (PAR)
NCT01697956 ·Status: COMPLETED ·Phase: PHASE3
-
Dose Selection Study of Efficacy and Safety of Different Doses of Grass MATA MPL and Grass MATA Using mEECs™
NCT02582073 ·Status: COMPLETED ·Phase: PHASE2
-
Biological Standardization of Allergen Extracts of Pollens of Betula Pendula, Phleum Pratense and Mite Extract of Dermatophagoides Pteronyssinus
NCT01147159 ·Status: COMPLETED ·Phase: PHASE2
-
Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis
NCT00387478 ·Status: TERMINATED ·Phase: PHASE2
-
Multicenter Trial of Sublingual Immunotherapy With a Solution of Grass Pollen Allergen Extract in Children
NCT00841256 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Specific Immunotherapy With CLUSTOID Grass Pollen
NCT01012531 ·Status: COMPLETED ·Phase: PHASE3
-
Multicenter, Double-blind, Randomized, Placebo-controlled Study of Mometasone Furoate Nasal Spray in Pediatric Subjects With Perennial Allergic Rhinitis (Study P06332)
NCT01135134 ·Status: COMPLETED ·Phase: PHASE3
-
Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Tree Pollen Allergy Vaccine
NCT00118625 ·Status: COMPLETED ·Phase: PHASE2
-
Dose Finding Study for Depigoid Birch: 4 Doses in Patients With Allergic Rhinitis/Rhinoconjunctivitis +-Asthma
NCT01144429 ·Status: COMPLETED ·Phase: PHASE2
-
Study Of Perennial Allergic Rhinitis In Pediatrics
NCT00253058 ·Status: COMPLETED ·Phase: PHASE3
-
Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Adult and Adolescent Subjects With Perennial Allergic Rhinitis (PAR)
NCT01133626 ·Status: COMPLETED ·Phase: PHASE3
-
Biological Standarization of Cupressus Arizonica Allergen Extract to Determine the Biological Activity in Histamine Equivalent Units (HEP)
NCT02512653 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Mometasone Furoate Nasal Spray in Perennial Allergic Rhinitis (Study P03748)(COMPLETED)
NCT00779545 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Pharmacology Study of MT-2990 in Seasonal Allergic Rhinitis Patients
NCT03570957 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Phenylephrine Extended-Release Tablets on Allergy-Related Nasal Congestion (P08498 AM1)
NCT01413958 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Bencycloquidium Bromide Nasal Spray in the Treatment of Moderate-severe Persistent Allergic Rhinitis
NCT05038202 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4