JAB-BX102 Monotherapy and Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
NCT05174585 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 21
Last updated 2026-01-06
Summary
This study is to evaluate the safety and tolerability of JAB-BX102 monotherapy and combination therapy with pembrolizumab in adult participants with advanced solid tumors.
Conditions
Interventions
- BIOLOGICAL
-
JAB-BX102 (anti-CD73 monoclonal antibody)
Administered by intravenous infusion (IV)
- BIOLOGICAL
-
pembrolizumab (anti-PD-1 monoclonal antibody)
Administered by intravenous infusion (IV)
Sponsors & Collaborators
- collaborator INDUSTRY
-
Jacobio Pharmaceuticals Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-08-18
- Primary Completion
- 2025-05-09
- Completion
- 2025-05-09
- FDA Drug
- Yes
Countries
- China
Study Locations
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