CPX-351 Real-World Effectiveness and Safety Study
NCT05169307 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 147
Last updated 2022-07-12
Summary
CPX-351 Real World Effectiveness and Safety Study (CREST UK) is a real-world evidence study designed to collect data on the potential benefits and/or risks of Vyxeos liposomal (liposomal daunorubicin/cytarabine; CPX-351) in routine clinical practice in the United Kingdom (UK).
Conditions
Interventions
- DRUG
-
CPX-351
This is a retrospective, non-interventional, observational study. No study drug will be administered in this study.
Sponsors & Collaborators
-
Iqvia Pty Ltd
collaborator INDUSTRY - lead INDUSTRY
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-01-14
- Primary Completion
- 2022-06-15
- Completion
- 2022-06-15
Countries
- United Kingdom
Study Locations
More Related Trials
-
Trial of CPX-351 in Adult Patients With First Relapse Acute Myeloid Leukemia (AML)
NCT00822094 ·Status: COMPLETED ·Phase: PHASE2
-
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old
NCT04269213 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia
NCT01696084 ·Status: COMPLETED ·Phase: PHASE3
-
Oral Azacitidine Maintenance Post-CPX 351
NCT06349239 ·Status: RECRUITING
-
CPX-351 in Patients Treated for Higher-risk Myelodysplastic Syndromes Experiencing Hypomethylating Agent Failure.
NCT04109690 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Investigator Initiated Trial of CPX-351 for Untreated Acute Myeloid Leukemia
NCT03335267 ·Status: COMPLETED ·Phase: PHASE2
-
Multicenter Study of CPX-351(Cytarabine:Daunorubicin) Liposome Injection in Patients With Advanced Hematologic Cancer.
NCT00389428 ·Status: COMPLETED ·Phase: PHASE1
-
Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
NCT04128748 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients
NCT02238925 ·Status: COMPLETED ·Phase: PHASE2
-
Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid Leukemia
NCT01804101 ·Status: COMPLETED ·Phase: NA
-
Trial of CPX-351 in Newly Diagnosed Elderly AML Patients
NCT00788892 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of CPX-351 in Children With Relapsed Leukemia or Lymphoma
NCT01943682 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic and Pharmacodynamic Assessment of Treatment With CPX-351 (Cytarabine: Daunorubicin) Liposome for Injection in Acute Leukemias and MDS Patients With Moderate Hepatic Impairment
NCT02269579 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Trial to Evaluate the Potential Impact of Renal Impairment on the Pharmacokinetics and Safety of CPX-351
NCT03555955 ·Status: COMPLETED ·Phase: PHASE1
-
CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomics
NCT05260528 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase I, Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia
NCT01756118 ·Status: COMPLETED ·Phase: PHASE1
-
Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia
NCT03629171 ·Status: RECRUITING ·Phase: PHASE2
-
CPX-351 in Higher Risk Myelodysplastic Syndromes
NCT04273802 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Safety and Tolerability of LBS-007 in Patients With Relapsed or Resistant Acute Leukaemias
NCT05756322 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Patients Receiving Induction With Liposomal Daunorubicin and Cytarabine (CPX-351) for Acute Myeloid Leukemia
NCT03988205 ·Status: TERMINATED ·Phase: PHASE4
-
CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS
NCT04668885 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias
NCT06994676 ·Status: RECRUITING ·Phase: PHASE1
-
Tazemetostat and Palbociclib With CPX-351for R/R AML
NCT05627232 ·Status: RECRUITING ·Phase: PHASE1
-
CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients
NCT04195945 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML
NCT06533761 ·Status: RECRUITING ·Phase: PHASE1