Trial Outcomes & Findings for Measuring Comfort and Clarity With Low Gain Feature in Pediatric Hearing Aid Users (NCT NCT05150964)

NCT ID: NCT05150964

Last Updated: 2023-05-19

Results Overview

A familiar spondee word list is presented at varying dB (decibel) levels. Threshold is defined as the lowest dB level at which a correct response occurs for two out of three ascending trials. Testing was completed in two, two-hour test sessions occurring two weeks apart. A different fitting prescription, NAL (National Acoustic Laboratory) or DSL (Desired Sensation Level) was selected for each test session, and counterbalanced across participants. Each session consisted of testing with the ASG (Adaptive Situational Gain) feature on and off. The lower the number (dB level), the softer the participant is able to repeat the words correctly two out of three times.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

16 participants

Primary outcome timeframe

Initial appointment (day 1 of study) and 2nd appointment (Day 14 of study)

Results posted on

2023-05-19

Participant Flow

Participant milestones

Participant milestones
Measure
Experimental
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. For certain speech tests the above conditions will apply but will include testing levels at both a louder level and a softer level. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Overall Study
STARTED
16
Overall Study
COMPLETED
14
Overall Study
NOT COMPLETED
2

Reasons for withdrawal

Reasons for withdrawal
Measure
Experimental
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. For certain speech tests the above conditions will apply but will include testing levels at both a louder level and a softer level. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Overall Study
Lost to Follow-up
2

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Experimental
n=16 Participants
One group will be fit with commercially available hearing aids that will have different program settings Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Age, Continuous
13.7 years
n=16 Participants
Sex: Female, Male
Female
8 Participants
n=16 Participants
Sex: Female, Male
Male
8 Participants
n=16 Participants
Region of Enrollment
United States
16 participants
n=16 Participants

PRIMARY outcome

Timeframe: Initial appointment (day 1 of study) and 2nd appointment (Day 14 of study)

Population: Participants who were fit with study hearing aids and completed at least one two-hour test session.

A familiar spondee word list is presented at varying dB (decibel) levels. Threshold is defined as the lowest dB level at which a correct response occurs for two out of three ascending trials. Testing was completed in two, two-hour test sessions occurring two weeks apart. A different fitting prescription, NAL (National Acoustic Laboratory) or DSL (Desired Sensation Level) was selected for each test session, and counterbalanced across participants. Each session consisted of testing with the ASG (Adaptive Situational Gain) feature on and off. The lower the number (dB level), the softer the participant is able to repeat the words correctly two out of three times.

Outcome measures

Outcome measures
Measure
Experimental
n=15 Participants
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Speech Reception Threshold
NAL Fitting with ASG Off
27 dB HL (decibels hearing level)
Standard Deviation 8
Speech Reception Threshold
NAL Fitting with ASG ON
27 dB HL (decibels hearing level)
Standard Deviation 7
Speech Reception Threshold
DSL Fitting with ASG Off
24 dB HL (decibels hearing level)
Standard Deviation 8
Speech Reception Threshold
DSL Fitting with ASG On
24 dB HL (decibels hearing level)
Standard Deviation 6

PRIMARY outcome

Timeframe: Initial appointment (Day 1 of study) and 2nd appointment (day 14 of study)

Population: Participants who were fit with study hearing aids and completed at least one two-hour test session.

Familiar monosyllabic word list presented at 40 dB and 70 dB. Percentage of words correctly repeated is calculated. Testing was completed in two, two-hour test sessions occurring two weeks apart. A different fitting prescription, NAL (National Acoustic Laboratory) or DSL (Desired Sensation Level) was selected for each test session and counterbalanced across participants such that one test session consisted of testing with one prescription, either NAL or DSL, but with both levels (40 and 70 dB) and with both ASG (Adaptive Situational Gain) settings, on and off. The higher the score, the better the word recognition in each condition.

Outcome measures

Outcome measures
Measure
Experimental
n=15 Participants
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct at 40 dB, NAL fitting, ASG Off
52 percentage of words correctly repeated
Standard Deviation 24
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct at 40 dB, NAL fitting, ASG On
63 percentage of words correctly repeated
Standard Deviation 26
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct at 40 dB, DSL fitting, ASG Off
69 percentage of words correctly repeated
Standard Deviation 21
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct at 40 dB, DSL fitting, ASG On
75 percentage of words correctly repeated
Standard Deviation 22
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct at 70 dB, NAL fitting, ASG Off
92 percentage of words correctly repeated
Standard Deviation 10
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct at 70 dB, NAL fitting, ASG On
95 percentage of words correctly repeated
Standard Deviation 5
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct at 70 dB, DSL fitting, ASG Off
95 percentage of words correctly repeated
Standard Deviation 6
Word Recognition Score With Words Presented at 40 dB SPL (Decibel Sound Pressure Level) and 70 dB SPL.
% correct, DSL fitting, ASG On
96 percentage of words correctly repeated
Standard Deviation 7

PRIMARY outcome

Timeframe: Initial appointment (Day 1 of study) and 2nd appointment (Day 14 of study)

Population: Participants who were fit with study hearing aids and completed at least one two-hour test session.

Out of a list of seven words, the participant repeats back as many words as they can recall. Percentage of correct words repeated back is calculated. Testing was completed in two, two-hour test sessions occurring two weeks apart. One fitting prescription, NAL (National Acoustic Laboratory) or DSL (Desired Sensation Level) was selected for each test session and counterbalanced across participants such that one test session consisted of testing with one prescription, either NAL or DSL, but with both levels (40 and 70 dB) and with both ASG (Adaptive Situational Gain) settings, on and off. A higher percentage score indicates better multi-word recognition.

Outcome measures

Outcome measures
Measure
Experimental
n=15 Participants
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 70 dB, DSL fitting, ASG On
67 percentage of words correctly repeated
Standard Deviation 13
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 40 dB for NAL fitting, ASG Off
48 percentage of words correctly repeated
Standard Deviation 20
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 40 dB for NAL fitting, ASG On
56 percentage of words correctly repeated
Standard Deviation 16
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 40 dB for DSL fitting, ASG Off
51 percentage of words correctly repeated
Standard Deviation 16
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 40 dB for DSL fitting, ASG On
54 percentage of words correctly repeated
Standard Deviation 16
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 70 dB, NAL fitting, ASG Off
66 percentage of words correctly repeated
Standard Deviation 17
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 70 dB, NAL fitting, ASG On
67 percentage of words correctly repeated
Standard Deviation 13
Multi-word Recognition at 40 dB SPL and 70 dB SPL
% correct at 70 dB, DSL fitting, ASG Off
63 percentage of words correctly repeated
Standard Deviation 13

PRIMARY outcome

Timeframe: Initial appointment (Day 1 of study) and 2nd appointment (day 14 of study)

Population: Participants who were fit with study hearing aids and completed at least one two-hour test session.

A list of 10 3-word phrases are presented to the participant. The participant indicates if the phrase contains a nonsense word by selecting the numbered response button (i.e. "1", "2", or "3") that corresponds to the position oof the nonsense word in the phrase. Testing was completed in two, two-hour test sessions occurring two weeks apart. A different fitting prescription, NAL (National Acoustic Laboratory) or DSL (Desired Sensation Level) was selected for each test session and counterbalanced across participants such that one test session consisted of testing with one prescription, either NAL or DSL, but with both levels (40 and 70 dB) and with both ASG (Adaptive Situational Gain) settings, on and off. . The score is the percent correct, a higher score is better.

Outcome measures

Outcome measures
Measure
Experimental
n=15 Participants
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, NAL fitting formula, ASG Off
65 percentage of correct responses
Standard Deviation 15
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, NAL fitting with ASG On
68 percentage of correct responses
Standard Deviation 13
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, DSL fitting, ASG Off
73 percentage of correct responses
Standard Deviation 18
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, DSL fitting, ASG On
71 percentage of correct responses
Standard Deviation 12
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, NAL fitting, ASG Off
89 percentage of correct responses
Standard Deviation 7
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, NAL fitting, ASG On
87 percentage of correct responses
Standard Deviation 7
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, DSL fitting, ASG Off
88 percentage of correct responses
Standard Deviation 9
Nonword Detection Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, DSL fitting, ASG On
87 percentage of correct responses
Standard Deviation 7

PRIMARY outcome

Timeframe: Initial appointment (Day 1 of study) and 2nd appointment (day 14 of study)

Population: Participants who were fit with study hearing aids and completed at least one two-hour test session.

A word learning task used to determine participant's ability to associate novel/nonsense words with novel images as rapidly as possible. Five nonsense words are paired with five novel images displayed on response buttons. The words are presented randomly 10 times each. The participant selects one picture per word. Scores are presented as percent correct. A higher percentage indicates better word learning. Testing was completed in two, two-hour test sessions occurring two weeks apart. A different prescription, NAL (National Acoustic Laboratory) or DSL (Desired Sensation Level) was selected for each test session and counterbalanced across participants such that one test session consisted of testing with one prescription, either NAL or DSL, but with both levels (40 and 70 dB) and with both ASG (Adaptive Situational Gain) settings, on and off.

Outcome measures

Outcome measures
Measure
Experimental
n=15 Participants
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, NAL fitting, ASG Off
68 percentage of correct responses
Standard Deviation 23
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, NAL fitting, ASG On
76 percentage of correct responses
Standard Deviation 18
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, DSL fitting, ASG Off
70 percentage of correct responses
Standard Deviation 22
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 40 dB, DSL fitting, ASG On
73 percentage of correct responses
Standard Deviation 20
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, NAL fitting, ASG Off
69 percentage of correct responses
Standard Deviation 18
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, NAL fitting, ASG On
73 percentage of correct responses
Standard Deviation 16
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, DSL fitting, ASG Off
67 percentage of correct responses
Standard Deviation 20
Rapid Word Learning With Stimuli Presented at 40 dB SPL and at 70 dB SPL.
% correct at 70 dB, DSL fitting, ASG On
70 percentage of correct responses
Standard Deviation 21

PRIMARY outcome

Timeframe: 2nd appointment (day 14 of study)

Population: Participants who were fit with study hearing aids and completed both two-hour test sessions.

Participants will rank preference for the ASG feature (either on or off) in each fitting (NAL and DSL) after listening to audio file.

Outcome measures

Outcome measures
Measure
Experimental
n=14 Participants
One group will be fit with commercially available hearing aids that will have different program settings. Each participant will be tested with the study hearing devices in the following conditions: 1. Hearing device programmed with the NAL (National Acoustic Laboratory) fitting prescription and with the ASG feature both on and off. 2. Hearing device programmed with the DSL (Desired Sensation Level) fitting prescription and with the ASG feature both on and off. Phonak Audeo hearing aid: receiver in the canal devices with non-custom earmolds
Subjective Preference for the Adaptive Situational Gain Feature With Each Fitting Formula
Number of participants preferring ASG Off with NAL fitting
2 Participants
Subjective Preference for the Adaptive Situational Gain Feature With Each Fitting Formula
Number of participants preferring ASG On with NAL fitting
2 Participants
Subjective Preference for the Adaptive Situational Gain Feature With Each Fitting Formula
Number of participants preferring ASG Off with DSL fitting
7 Participants
Subjective Preference for the Adaptive Situational Gain Feature With Each Fitting Formula
Number of participants preferring ASG On with DSL fitting
3 Participants

Adverse Events

Experimental

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Director of Clinical Research

Sonova USCS

Phone: 630-821-5000

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place