Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor
NCT05150106 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 165
Last updated 2025-12-02
Summary
The researchers will systematically evaluate current and novel clinical voice assessment tools and measures to elucidate distinct clinical phenotypes of those with laryngeal dystonia and voice tremor.
Conditions
- Laryngeal Dystonia
- Spasmodic Dysphonia
- Tremor
Interventions
- OTHER
-
Clinical assessments of laryngeal function
Participants will undergo acoustic, aerodynamic, respiratory kinematic, nasoendoscopic, and laryngeal EMG recordings, as well as real-time MRI of the upper airway for comprehensive characterization of shared and distinct features of laryngeal dystonia and voice tremor.
Sponsors & Collaborators
- collaborator OTHER
-
Massachusetts Eye and Ear Infirmary
lead OTHER
Principal Investigators
-
Kristina Simonyan, MD, PhD · Massachusetts Eye and Ear
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-11-07
- Primary Completion
- 2027-08-31
- Completion
- 2027-08-31
Countries
- United States
Study Locations
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