Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor

NCT05150106 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 165

Last updated 2025-12-02

No results posted yet for this study

Summary

The researchers will systematically evaluate current and novel clinical voice assessment tools and measures to elucidate distinct clinical phenotypes of those with laryngeal dystonia and voice tremor.

Conditions

  • Laryngeal Dystonia
  • Spasmodic Dysphonia
  • Tremor

Interventions

OTHER

Clinical assessments of laryngeal function

Participants will undergo acoustic, aerodynamic, respiratory kinematic, nasoendoscopic, and laryngeal EMG recordings, as well as real-time MRI of the upper airway for comprehensive characterization of shared and distinct features of laryngeal dystonia and voice tremor.

Sponsors & Collaborators

Principal Investigators

  • Kristina Simonyan, MD, PhD · Massachusetts Eye and Ear

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-11-07
Primary Completion
2027-08-31
Completion
2027-08-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05150106 on ClinicalTrials.gov