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Tracking Biomarkers of Speech Intelligibility

NCT05145946 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2025-12-18

No results posted yet for this study

Summary

Difficulties understanding speech in noisy environments repeatedly coincide with high-frequency hearing loss. This complaint is commonly exhibited in adults in middle/older age who have a history of noise exposure. In this study, an immersive audiomotor training game will be utilized to drive improvements in speech intelligibility, controlled by an auditory memory training game. Physiological measures will be tracked that could inform clinical assessment of hearing in noise abilities.

Conditions

  • High-Frequency Hearing Loss

Interventions

BEHAVIORAL

Video Game Training Group 1

Closed-loop audiomotor game. Home-based training sessions for 3.5 hours per week over an 8-week.

BEHAVIORAL

Video Game Training Group 2

Auditory memory game. Home-based training sessions for 3.5 hours per week over an 8-week.

Sponsors & Collaborators

  • Massachusetts Eye and Ear Infirmary

    lead OTHER

Principal Investigators

  • Daniel B Polley, Ph.D. · Massachusetts Eye and Ear Infirmary

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
69 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-31
Primary Completion
2022-12-31
Completion
2022-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05145946 on ClinicalTrials.gov