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Serum-Protein-Based Indices for the Progression of Fracture Healing and Nonunion

NCT05143476 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2026-02-27

No results posted yet for this study

Summary

To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific correlation with later radiological and functional signs used to define delayed healing and non-union.

Conditions

  • Humerus Fractures

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED

  • Major Extremity Trauma Research Consortium

    lead OTHER

Principal Investigators

  • Louis Gerstenfeld, PhD · Boston University

  • Renan C Castillo, PhD · Johns Hopkins Bloomberg School of Public Health

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-06-26
Primary Completion
2024-05-02
Completion
2024-10-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05143476 on ClinicalTrials.gov