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Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations

NCT05140499 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2026-01-27

Study results available
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Summary

Through this pilot prospective trial, we aim to obtain preliminary data investigating the effectiveness of perineural catheters and liposomal bupivacaine, both currently accepted as standard care at Maine Medical Center, for the management of post-limb amputation pain. We will use the data that we collect to inform the design of a larger, appropriately powered study.

Conditions

  • Pain, Postoperative
  • Amputation

Interventions

DRUG

Liposomal bupivacaine

Popliteal nerve block

DRUG

Bupivacaine Hydrochloride 0.5 % Injectable Solution

Continuous nerve catheter

Sponsors & Collaborators

  • MaineHealth

    collaborator OTHER

  • Aurora Quaye

    lead OTHER

Principal Investigators

  • Aurora Quaye, MD · MaineHealth

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-15
Primary Completion
2025-11-20
Completion
2025-12-23
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05140499 on ClinicalTrials.gov