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Intestinal Microbiota Composition in Patients With Chronic Pancreatitis and Pancreatic Exocrine Insufficiency

NCT05132309 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 96

Last updated 2021-11-24

No results posted yet for this study

Summary

Assessment of qualitative and quantitative composition of the intestinal microbiota in patients with CP; in patients with CP and PEI complication of mild to severe degree; patients with CP and PEI who underwent surgical intervention on the pancreas. Intergroup comparison of the microbial compositional characteristics and their analysis. Correction of enzyme replacement therapy in selected groups of patients with regard to the identified microbial characteristics. Assessment of the intestinal microbiota composition in dynamics after 6 (+1) months on the background of allocated therapy

Conditions

  • Chronic Pancreatitis
  • Pancreatic Exocrine Insufficiency

Interventions

COMBINATION_PRODUCT

enzyme replacement therapy

Correction of the previously prescribed dose of enzyme replacement therapy (ERT)/first time selection of ERT according to the severity of pancreatic exocrine insufficiency

Sponsors & Collaborators

  • Moscow State University of Medicine and Dentistry

    collaborator OTHER

  • Federal Research and Clinical Center of Physical-Chemical Medicine

    lead OTHER

Principal Investigators

  • Elena Ilina, Prof · Federal Research and Clinical Center of Physical-Chemical Medicine

  • Igor Maev, Prof · Moscow State University of Medicine and Dentistry

Eligibility

Min Age
23 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-01
Primary Completion
2021-07-01
Completion
2021-07-01

Countries

  • Russia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05132309 on ClinicalTrials.gov