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Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease

NCT05122598 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2022-05-17

No results posted yet for this study

Summary

The purpose of this study is to determine whether daily treatment with this new treatment approach, called COT would be effective in protecting the memory and brain regions of people who are already showing signs of memory loss.

Conditions

Interventions

DRUG

COT

The COT with proprietary odorant molecules is designed to stimulate olfactory neural activity over long periods of time combined with orbitofrontal cortex (OFC) dependent olfactory tasks.

DRUG

Sham

Sham COT uses artificially scented compressed room air instead of olfactory stimulants and has control cognitive olfactory tasks.

Sponsors & Collaborators

  • Howard University

    collaborator OTHER

  • Family and Medical Counseling Service, Inc

    collaborator UNKNOWN

  • Medical Home Development Group

    collaborator UNKNOWN

  • National Institute on Aging (NIA)

    collaborator NIH

  • Johns Hopkins University

    collaborator OTHER

  • Evon Medics LLC

    lead INDUSTRY

Principal Investigators

  • Evaristus Nwulia, MD · Evon Medics LLC

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
55 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-15
Primary Completion
2023-04-01
Completion
2023-04-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05122598 on ClinicalTrials.gov