Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells
NCT05120518 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2024-11-12
Summary
The objective of this study is to utilize all donated pediatric tumor tissues and cells obtained from autopsy to prospectively develop novel patient derived orthotopic xenograft (PDOX) mouse models as well as in vitro cell culture model systems for pediatric cancers, and also provide tissue samples to other researchers and organizations (eg, CBTN, DIPG Registry, COG).
Conditions
- Pediatric Cancer
Interventions
- OTHER
-
Collection of post mortem tissue donation
Collection of post mortem tissue from pediatric participants with cancer and non-cancer tumor types from whom post mortem tissue donation and autopsy consent is obtained.
Sponsors & Collaborators
-
Ann & Robert H Lurie Children's Hospital of Chicago
lead OTHER
Principal Investigators
-
Angela Waanders, MD · Ann & Robert H Lurie Children's Hospital of Chicago
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-08-14
- Primary Completion
- 2029-08-14
- Completion
- 2029-08-14
Countries
- United States
Study Locations
More Related Trials
-
Dissecting Tumour MicroenvirOnment in Solid Paediatric Tumour to Improve Adoptive Cell Therapy
NCT07240207 ·Status: RECRUITING
-
Pediatric Solid Tumor Metabolism [A Prospective Study Exploring Metabolism of Solid Tumors in Pediatrics]
NCT03686566 ·Status: COMPLETED
-
A Prediction Model of Hematological Recovery After High-dose Chemotherapy in Pediatric Solid Tumor
NCT05024331 ·Status: COMPLETED
-
Paclitaxel/Ifosfamide/Cisplatin Chemotherapy for High Risk Pediatric Germ Cell Tumor
NCT05455918 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors
NCT02536183 ·Status: TERMINATED ·Phase: PHASE1
-
A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy
NCT04478292 ·Status: RECRUITING ·Phase: PHASE3
-
Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma
NCT00923351 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors
NCT05135975 ·Status: RECRUITING ·Phase: PHASE2
-
A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
NCT05634369 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Mobilization by Plerixafor of Haematopoietic Stem Cells in Children
NCT01225419 ·Status: COMPLETED ·Phase: PHASE2
-
Pulmonary Function at Presentation and Follow-up in Hemato-Oncology 3-7 Years Old Children
NCT00552825 ·Status: COMPLETED
-
Trabectedin and Irinotecan for Refractory Pediatric Sarcomas
NCT02509234 ·Status: UNKNOWN
-
A Multiple Ascending Dose Study of R1507 in Children and Adolescents With Advanced Solid Tumors.
NCT00560144 ·Status: COMPLETED ·Phase: PHASE1
-
Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells
NCT07148050 ·Status: RECRUITING ·Phase: PHASE1
-
Salvage Therapy With Chemotherapy and Natural Killer Cells in Relapsed/Refractory Paediatric T Cell Lymphoblastic Leukaemia and Lymphoma
NCT01944982 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children
NCT06235125 ·Status: RECRUITING ·Phase: PHASE1
-
Panitumumab in Children With Solid Tumors
NCT00658658 ·Status: COMPLETED ·Phase: PHASE1
-
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
NCT03618381 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Cardiometabolic Status in Childhood Acute Lymphoblastic Leukemia
NCT01688752 ·Status: WITHDRAWN
-
Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models
NCT06822842 ·Status: NOT_YET_RECRUITING
-
Malignant Pediatric Soft Tissue & Bone Tumors of the Extremities: A Retrospective Study
NCT02557243 ·Status: COMPLETED
-
Tissue Study of Bv8/PK-2 Inhibition in Human Cancer
NCT01656824 ·Status: UNKNOWN
-
A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomas
NCT00001564 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors
NCT04774718 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients
NCT01169584 ·Status: COMPLETED ·Phase: PHASE1