Nitazoxanide Pharmacokinetic Parameters in Hepatic Impaired Patients
NCT05116826 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2022-10-14
Summary
This study is being conducted to evaluate the major Nitazoxanide (NTZ) active metabolite in adult participants with hepatic impairment and healthy adults.
Conditions
- Moderate Hepatic Impairment
- Severe Hepatic Impairment
- Liver Diseases
Interventions
- DRUG
-
Nitazoxanide
500 mg Twice Daily for 7 days
Sponsors & Collaborators
-
Genfit
lead INDUSTRY
Principal Investigators
-
Carol Addy, MD · Genfit
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-11-05
- Primary Completion
- 2022-04-08
- Completion
- 2022-04-13
- FDA Drug
- Yes
Countries
- United States
Study Locations
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