Effect of Testosterone Treatment on Drug Metabolism and Transport
NCT05116293 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14
Last updated 2026-05-04
Summary
This project will evaluate the effect of gender-affirming testosterone treatment on how other medications are processed by the body.
Conditions
- Transgender Persons
Interventions
- DRUG
-
Midazolam oral solution
Oral syrup
- DRUG
-
Digoxin Oral Tablet
Oral tablet
- DRUG
-
Acetaminophen Oral Tablet
Oral tablet
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Lauren Cirrincione, MPH,Pharm D · University of Washington
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-05-01
- Primary Completion
- 2024-02-15
- Completion
- 2025-12-31
Countries
- United States
Study Locations
More Related Trials
-
Hormone Secretion in Transgender Males
NCT04321551 ·Status: WITHDRAWN ·Phase: PHASE4
-
Transgender In Transition
NCT04028219 ·Status: RECRUITING
-
ORAL T-8 Oral Testosterone for Male Hormonal Contraception
NCT01167829 ·Status: COMPLETED ·Phase: PHASE1
-
Metabolomics During Testosterone Therapy
NCT01963390 ·Status: COMPLETED
-
Effect of Progesterone on Testosterone Concentrations and Breast Development in Transwomen
NCT04534881 ·Status: TERMINATED ·Phase: PHASE2
-
Testosterone and Its Metabolites in GID
NCT00146146 ·Status: COMPLETED ·Phase: PHASE3
-
T-IR- Study to Understand the Effects of Testosterone and Estrogen on the Body's Response to the Hormone Insulin
NCT01686828 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
TDSM- Testosterone Dose Response in Surgically Menopausal Women
NCT00494208 ·Status: COMPLETED ·Phase: NA
-
ORAL T-6: Oral Androgens in Man-6
NCT00663793 ·Status: COMPLETED ·Phase: PHASE1
-
Oral T7 Oral Testosterone in Man
NCT00842751 ·Status: COMPLETED ·Phase: PHASE2
-
Transgender Men, Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINIC
NCT04254354 ·Status: RECRUITING
-
Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version
NCT07092527 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of Hormone Therapy on Renal Function
NCT04482920 ·Status: COMPLETED
-
Testosterone Replacement in Metabolic Syndrome and Inflammation
NCT01123278 ·Status: COMPLETED ·Phase: PHASE4
-
CEP-1 Hormonal Regulation of Circulating Endothelial Progenitor Cells and HDL-C in Men
NCT00729859 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Men
NCT04237467 ·Status: COMPLETED
-
Dose Titration Investigation of the Pharmacokinetics of Testosterone Transdermal Systems in Hypogonadal Men
NCT01104246 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Testosterone and Fat Utilization
NCT03289559 ·Status: COMPLETED ·Phase: NA
-
Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency
NCT03716739 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Increasing Testosterone on Insulin Sensitivity in Men With the Metabolic Syndrome
NCT00438321 ·Status: TERMINATED ·Phase: PHASE1
-
Effects of Testosterone Plus Dutasteride or Placebo on Muscle Strength, Body Composition and Metabolism in Transmen
NCT04545450 ·Status: COMPLETED ·Phase: PHASE3
-
Assessing the Safety/Efficacy of Transdermal Testosterone in Female Patients With Symptomatic Heart Failure
NCT00957034 ·Status: TERMINATED ·Phase: PHASE2
-
Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17
NCT06312761 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
The Effects of Testosterone and Nutritional Supplementation in the Undernourished Elderly
NCT00117000 ·Status: UNKNOWN ·Phase: PHASE3
-
Testosterone and Pain Sensitivity
NCT01689896 ·Status: WITHDRAWN ·Phase: PHASE4