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Alternate Day vs. Daily Iron Supplementation in Iron Depleted Women

NCT05105438 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2024-01-24

No results posted yet for this study

Summary

Iron deficiency (ID) with or without anemia is a major public health problem worldwide, especially in women of reproductive age. Iron supplementation can be an effective strategy to prevent and treat ID and iron deficiency anemia (IDA). Recent studies suggests that giving oral iron every other day would be an optimized dosing regimen with maximized absorption and a lower incidence of gastrointestinal side effects compared to consecutive day dosing. Long-term trials in which participants and investigators are blinded to the dosing interval with iron status and gastrointestinal side effects as study outcomes are needed.

Conditions

Interventions

DIETARY_SUPPLEMENT

Consecutive Day Dosing

100 mg iron as FeSO4 daily for 3 months, followed by matched placebo daily for 3 months.

DIETARY_SUPPLEMENT

Alternate Day Dosing

100 mg iron as FeSO4 and matched placebo on alternating days for 6 months.

Sponsors & Collaborators

  • Swiss Federal Institute of Technology

    lead OTHER

Principal Investigators

  • Nicole Stoffel, Dr. · Human Nutrition Laboratory, ETH Zuerich

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-12-16
Primary Completion
2022-08-10
Completion
2022-12-08

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05105438 on ClinicalTrials.gov