High Versus Low Blood-Pressure Target in the Post Operative Care of Liver Transplantation A Randomized, Controled, Open and Unicentric Trial.
NCT05068713 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 174
Last updated 2024-01-17
Summary
LIVER PAM
A randomized, controled, open and unicentric trial comparing high (MAP 85-90 mmHg) and low (65-70 mmHg) target of mean arterial pressure in the first 24 hours after liver transplantation.
Conditions
- Liver Transplant; Complications
Interventions
- OTHER
-
Usual Care + High Target of Mean Arterial Pressure
Targeting the weaning of vasopressors to a mean arterial pressure of 85-90mmHg in the first 24h after liver trasnplant.
- OTHER
-
Usual Care
Targeting the weaning of vasopressors to a mean arterial pressure of 65-70mmHg in the first 24h after liver trasnplant.
Sponsors & Collaborators
-
University of Sao Paulo General Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-24
- Primary Completion
- 2024-01-05
- Completion
- 2024-01-05
Countries
- Brazil
Study Locations
More Related Trials
-
Perioperative Factors and Living Donor Liver Transplantation
NCT06312098 ·Status: NOT_YET_RECRUITING
-
Stroke Volume Variation Versus Central Venous Pressure Guidance for Reducing Perioperative Blood Loss During Open Liver Resection
NCT06905015 ·Status: RECRUITING ·Phase: NA
-
Dynamic Monitor of Portacaval Pressure Gradient
NCT03590288 ·Status: COMPLETED
-
Predictive Factors for Massive Transfusion During Liver Transplantation
NCT05763446 ·Status: RECRUITING
-
Cardiac Output Optimization on Postoperative Complications in Major Hepatic Surgery
NCT04655885 ·Status: RECRUITING ·Phase: NA
-
Restrictive vs Goal Directed Fluid Therapy During Hepatobiliary Surgery
NCT04092608 ·Status: COMPLETED ·Phase: NA
-
Hepatic Hemodynamic Changes and Simulation in Living-Related Liver Transplantation
NCT00234624 ·Status: UNKNOWN
-
Intraoperative Blood Loss Under Standard Versus Low Pneumoperitoneum Pressure During Laparoscopic Liver Resection.
NCT06060899 ·Status: COMPLETED ·Phase: NA
-
Perioperative Individualized Optimization of Mean Arterial Pressure in Cardiac Surgery
NCT05403697 ·Status: TERMINATED ·Phase: NA
-
Effect of High vs. Low MAP Levels on Clinical Outcomes in Elderly Patients During Noncardiothoracic Surgery
NCT02857153 ·Status: UNKNOWN ·Phase: NA
-
Hypotension Prediction Index in Living Donor Liver Transplantation
NCT05010941 ·Status: COMPLETED
-
Magnesium Administration in Liver Transplantation and Reperfusion Injury
NCT00994981 ·Status: COMPLETED ·Phase: PHASE4
-
"Duration of Preoperative Clear Fluids Fasting in Patients Undergoing Liver Transplant"
NCT07288281 ·Status: RECRUITING
-
Perioperative Personalized Blood Pressure Management
NCT04894045 ·Status: COMPLETED ·Phase: NA
-
Dynamic Preload Parameters During Liver Transplantation
NCT01971333 ·Status: UNKNOWN
-
Effect of Rapid Transfusion With Fluid Management System (FMS) on Plasma Potassium in Liver Transplantation Recipients
NCT01331889 ·Status: COMPLETED
-
Vasodilator-induced Hypovolemia in Living Liver Donors
NCT02033967 ·Status: COMPLETED ·Phase: NA
-
High Versus Low Pneumoperitoneum PressUre for Parenchymal Transection in Minimally Invasive Major Liver Surgery
NCT06770803 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Restrictive- vs Individualized Goal Directed Fluid Therapy in Liver Surgery
NCT05704387 ·Status: COMPLETED ·Phase: NA
-
Impact of Positive End-expiratory Pressure on Hepatic Venous Flow
NCT02700581 ·Status: UNKNOWN ·Phase: NA
-
Perioperative Personalized Blood Pressure Management: IMPROVE-multi
NCT05416944 ·Status: COMPLETED ·Phase: NA
-
The Effect of Remote Ischemic Preconditioning in Patients Undergoing Major Liver Surgery
NCT00796588 ·Status: UNKNOWN ·Phase: NA
-
Response of Cardiovascular Parameters to Physical Therapy Post Liver Transplantation
NCT05514743 ·Status: COMPLETED ·Phase: NA
-
Perioperative Blood Transfusion in Open Liver Resection
NCT06189911 ·Status: COMPLETED
-
Prediction Model of the Blood Pressure Response to the Administration of Fluids in Abdominal Surgery Using the Pram Method.
NCT04594174 ·Status: UNKNOWN