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Sound and Music for Mild Cognitive Impairment

NCT05064007 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2025-08-29

Study results available
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Summary

Emerging studies in humans found that 40 Hz sound induces neural gamma oscillation and enhanced cognitive function in older adults with and without Alzheimer's Disease. We will compare a 40 Hz music intervention to both 40 Hz sound and music alone in a clinical cohort of older adults with mild cognitive impairment.

Conditions

Interventions

BEHAVIORAL

A: 40 Hz music

The participant will listen to the 40 Hz music playlist one hour each day, 5 days a week for 4 weeks

BEHAVIORAL

B: 40 Hz sound

The participant will listen to the 40 Hz sound playlist one hour each day, 5 days a week for 4 weeks

BEHAVIORAL

C: Preferred music

The participant will listen to the preferred music playlist one hour each day, 5 days a week for 4 weeks

Sponsors & Collaborators

Principal Investigators

  • JUNXIN LI, PhD · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
50 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-02-01
Primary Completion
2024-04-03
Completion
2025-04-03

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05064007 on ClinicalTrials.gov