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Effect of Using Dextrose-containing Intraoperative Fluid in Children

NCT05061836 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 68

Last updated 2021-09-30

No results posted yet for this study

Summary

The glucose-containing fluid was preferred for maintenance fluid in pediatric surgery to prevent hypoglycemic events. This practice can lead to intraoperative hyperglycemia which can induce osmotic diuresis and consequently dehydration and electrolyte disturbances.

As an anesthesiologist, the use of glucose-containing fluid should be reconsidered to avoid these undesirable effects in pediatric surgery.

Our study aims to identify an appropriate use of 5% dextrose containing solution during intraoperative period in children (2 age groups: 1-2 vs 3-5 years old) that can prevent glucose and lipid mobilization without causing hypo/hyperglycemia and provide adequate fluid maintenance in the context of hospitals in Thailand

Conditions

  • Pediatric Surgery

Interventions

DRUG

Ringer acetate

Patient will receive Acetate Ringer's solution (Acetar) infused at maintenance rate

DRUG

1.25%Dextrose equivalence

5%dextrose in normal saline (5%DNSS) infused ¼ of maintenance rate

DRUG

2.5%Dextrose equivalence

5%dextrose in normal saline (5%DNSS) infused ½ of maintenance rate

DRUG

Dextrose 5

5%dextrose in normal saline (5%DNSS) infused with maintenance rate

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
1 Year
Max Age
5 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-31
Primary Completion
2022-09-30
Completion
2022-12-31

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05061836 on ClinicalTrials.gov