Second-line Treatment of Primary Autoimmune Hemolytic Anemia
NCT05057468 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2025-03-20
Summary
the cyclosporine showed efficacy in many immune cytopenic diseases in the light of numerous case reports and retrospective data. This study compares cyclosporin versus rituximab in steroid-refractory anemia.
Conditions
- Primary Autoimmune Hemolytic Anemia
Interventions
- DRUG
-
Cyclosporine
2.5-5 mg orally for 3 months
- DRUG
-
375 mg/ m2 weekly dose for a maximum of 4 weeks
Sponsors & Collaborators
-
Assiut University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-10-20
- Primary Completion
- 2026-11-01
- Completion
- 2026-11-30
Countries
- Egypt
Study Locations
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