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Effect of Opioids on Central Control of Ventilation in Children With Obstructive Sleep Apnea

NCT05051189 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2025-04-06

No results posted yet for this study

Summary

Children OSA exhibit varying responses to opioids. It is unknown if the degree of intermittent hypoxemia results in different opioid sensitivity

Conditions

  • OSA
  • Opioid
  • Adenotonsillectomy

Interventions

DRUG

Fentanyl Citrate

Ventilatory response to fentanyl in patients with OSA Specifically: respiratory changes, CO2, RR, TV

Sponsors & Collaborators

  • University of Houston

    collaborator OTHER

  • Children's Hospital of Philadelphia

    collaborator OTHER

  • Wake Forest University

    collaborator OTHER

  • Baylor College of Medicine

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
2 Years
Max Age
8 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-01
Primary Completion
2024-11-01
Completion
2024-11-01
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05051189 on ClinicalTrials.gov