Efficacy of Apraclonidine Eye Drops in the Treatment of Ptosis Secondary to Myasthenia Gravis
NCT05045248 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2021-09-16
Summary
This study is aimed at assessing the efficacy of Apraclonidine eye drops in the treatment of ptosis secondary to myasthenia gravis.
Conditions
- Myasthenia Gravis
- Ocular Myasthenia Gravis
Interventions
- DRUG
-
Apraclonidine Hcl 0.5% Oph Soln
Each patient is administered 2 drops of Apraclonidine 0.5% solution to the most affected eye
Sponsors & Collaborators
-
American University of Beirut Medical Center
lead OTHER
Principal Investigators
-
Johnny Salameh, MD · American University of Beirut Medical Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-06-01
- Primary Completion
- 2021-04-15
- Completion
- 2021-04-15
- FDA Drug
- Yes
Countries
- Lebanon
Study Locations
More Related Trials
-
Pharmacodynamics of a Fixed Dose Combination of 0.34% Tropicamide and 2.5% Phenylephrine Hydrochloride, Eye Drop, Solution
NCT07075224 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis
NCT03097315 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety and Efficacy of Bimatoprost in Patients With Glaucoma or Ocular Hypertension
NCT00538304 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma
NCT00451152 ·Status: COMPLETED ·Phase: PHASE2
-
Ocular-hypertensive Response to Topical Steroids in Children After Bilateral Strabismus Surgery
NCT02816905 ·Status: COMPLETED ·Phase: PHASE4
-
A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT
NCT01654484 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis
NCT02595398 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy Study of Brimonidine in Patients With Glaucoma or Ocular Hypertension
NCT00652483 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation
NCT03751631 ·Status: COMPLETED ·Phase: PHASE3
-
Study of AR-13324 in Patients With Elevated Intraocular Pressure
NCT01528787 ·Status: COMPLETED ·Phase: PHASE2
-
A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertension
NCT00788541 ·Status: TERMINATED ·Phase: PHASE2
-
Nasal Steroids in Controlled Glaucoma
NCT00775489 ·Status: COMPLETED ·Phase: NA
-
Study on Effective Mydriasis in Premature Infants
NCT01054027 ·Status: COMPLETED ·Phase: NA
-
24-hour IOP-lowering Effect of 0.01% Bimatoprost
NCT01271686 ·Status: COMPLETED ·Phase: PHASE4
-
Single Dose of 1% Tropicamide and 10% Phenylephrine for Pupillary Dilation
NCT00120432 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular Hypertension
NCT00541242 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of a Glaucoma Drug Delivery System
NCT00824720 ·Status: COMPLETED ·Phase: PHASE2
-
Exploratory Study of Dipraglurant (ADX48621) for the Treatment of Patients With Blepharospasm
NCT05027997 ·Status: COMPLETED ·Phase: PHASE2
-
Pharmacokinetics of the Brimonidine Tartrate Posterior Segment Delivery System in Patients Undergoing Pars Plana Vitrectomy
NCT01229410 ·Status: COMPLETED ·Phase: PHASE1
-
Ocular Hypotensive Efficacy of AR-102
NCT00523250 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension
NCT01687426 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Pupil Dilation Speed With the MAP Dispenser
NCT04907474 ·Status: COMPLETED ·Phase: PHASE4
-
Anecortave Acetate in Patients With Open-angle Glaucoma
NCT00320203 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia
NCT03804268 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)
NCT05134974 ·Status: COMPLETED ·Phase: PHASE3