Trial Outcomes & Findings for Epidemiological Study of the COVID-2019 in Participating Organizations. (NCT NCT05043142)

Race and Ethnicity were not collected from any participant.

The incidence of COVID-2019 cases in participating organizations by which study subjects are employed (SI National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky; Yuria-Pharm LLC; Infuzia PJSC; Institute Hyalual LLC; Medical Center M.T.K. LLC; InterChem SLC; Diatom LLC). .

The severity of the COVID-2019 cases in participating organizations by which study subjects are employed (SI National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky; Yuria-Pharm LLC; Infuzia PJSC; Institute Hyalual LLC; Medical Center M.T.K. LLC; InterChem SLC; Diatom LLC).

Prevention methods of SARS, including COVID-2019, which were used by subject that had at least one COVID-2019 case. The number of participants is reported for every prevention method separately.

Prevention methods of SARS, including COVID-2019, which were used by subject that did not have any COVID-2019 case. The number of participants is reported for every prevention method separately.

Relationship between the used prevention methods and iand the Risk to Have at Least One Case of COVID-2019. among staff of participating organizations.Prevention methods within this outcome includes all prevention methods which were used by subjects. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between the presence of comorbidities, such as bronchial asthma and COPD (Chronic obstructive pulmonary disease), and the risk to have at least one case of COVID-2019. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between the COVID-2019 case and the risk of change of the course of comorbidities, such as bronchial asthma and сhronic obstructive pulmonary disease (COPD). Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between different strategies and combinations of drugs used for prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between different strategies and combinations of drugs used for prophylactics at any time from March 2020 and the risk of having a severe COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between different strategies and combinations of drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiseptics + oral systemic antiviral drugs + other drugs used for prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + immunomodulatory drugs + other drugs used for prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + oral systemic antiviral drugs + other drugs used for prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between oral systemic antiviral drugs + vitamins + other drugs used for prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between specific prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Specific prophylactics included inhalation antiseptics, inhalation antiviral drugs, oral systemic antiviral drugs, injectable systemic antiviral drugs, immunomodulatory drugs and antibiotics. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between nonspecific prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Nonspecific prophylactics included vitamins, herbal drugs, homeopathic drugs and other drugs. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between combined prophylactics at any time from March 2020 and the risk of having a COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiseptics + oral systemic antiviral drugs used for prophylactics at any time from March 2020 and the risk of having a severe COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + oral systemic antiviral drugs used for prophylactics at any time from March 2020 and the risk of having a severe COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between nonspecific prophylactics at any time from March 2020 and the risk of having a severe COVID-2019 case. Nonspecific prophylactics included vitamins, herbal drugs, homeopathic drugs and other drugs. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between specific prophylactics at any time from March 2020 and the risk of having a severe COVID-2019 case. Specific prophylactics included inhalation antiseptics, inhalation antiviral drugs, oral systemic antiviral drugs, injectable systemic antiviral drugs, immunomodulatory drugs and antibiotics. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between combined prophylactics at any time from March 2020 and the risk of having a severe COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between vitamins + herbal drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between vitamins + other drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiseptics + other drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + other drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between oral systemic antiviral drugs + herbal drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between immunomodulatory drugs + herbal drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiseptics + oral systemic antiviral drugs + vitamins used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiseptics + immunomodulatory drugs + vitamins used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiseptics + vitamins + other drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between immunomodulatory drugs + vitamins + herbal drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + oral systemic antiviral drugs + vitamins used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + immunomodulatory drugs + vitamins used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + vitamins + other drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between inhalation antiviral drugs + vitamins + herbal drugs used for prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between specific prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Specific prophylactics included inhalation antiseptics, inhalation antiviral drugs, oral systemic antiviral drugs, injectable systemic antiviral drugs, immunomodulatory drugs and antibiotics. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between nonspecific prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Nonspecific prophylactics included vitamins, herbal drugs, homeopathic drugs and other drugs. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.

Relationship between combined prophylactics at any time from March 2020 and the risk of hospitalization of persons who had at least one COVID-2019 case. Measure of outcome is risk ratio (RR), also called relative risk, compares the risk of a health event (disease, injury, risk factor, or death) among one group with the risk among another group. It does so by dividing the risk (incidence proportion, attack rate) in group 1 by the risk (incidence proportion, attack rate) in group 2. If the risk ratio is 1 (or close to 1), it suggests no difference or little difference in risk (incidence in each group is the same). A risk ratio \> 1 suggests an increased risk of that outcome in the exposed group. A risk ratio \< 1 suggests a reduced risk in the exposed group.